2012/05/21

Symptoms of renal failure symptoms


The symptoms of renal failure is divided into three, three clinical manifestations are different.
1, the starting period. This period, patients often suffer some of the ATN, known etiology,such as hypotension, ischemia, sepsis and renal toxins. Renal parenchymal damage buthas not yet occurred. At this stage of acute renal failure is preventable. But with thetubular epithelium was damaged, the GFR, a sudden drop in the performance of acute renal failure syndrome in the clinical became apparent, then enter the maintenance phase.
2, the maintenance period. Also known as oliguria. Typical for 7-14 days, but can also beas short as a few days, as long as 4-6 weeks. Glomerular rate remained at a low level.Many patients, there may be oliguria (<40Oml / d). But some patients can not oliguria,urine output more than 400ml / d, referred to as non-oliguric acute renal failure, thedisease mostly lighter, better prognosis. However, regardless of the amount of urinewhether the reduction in renal dysfunction, can be a series of clinical uremiaperformance. Infection is another common and serious complications of acute renal failure. Acute renal failure at the same time or in the development of the disease processcan also merge multiple organ failure, patient mortality can be as high as 70%.
3, the recovery period. Renal tubular cell regeneration, repair, restore tubular integrity.Glomerular filtration rate gradually returned to normal or near normal range. Oliguricpatients began to appear diuretic, how much urine the performance of daily urine outputup to 3000-5000ml or more. Usually lasts 1-3 weeks, then back to normal. Comparedwith the glomerular filtration rate, the recovery of the glomerular epithelial cell function(solute and water reabsorption) is relatively delayed, and often take several months afterrecovery. The small number of patients may be the ultimate legacy varying degrees ofrenal structural and functional defects.

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