Coffee or no Coffee

Coffee or no Coffee

Coffee is a brewed beverage with a dark, slightly acidic flavor prepared from the roasted seeds of the coffee plant, colloquially called coffee beans. The beans are found in coffee cherries, which grow on trees cultivated in over 70 countries, primarily in equatorial Latin America, Southeast Asia, South Asia and Africa. Green (unroasted) coffee is one of the most traded agricultural commodities in the world.[1] Coffee can have a stimulating effect on humans due to itscaffeine content. It is one of the most-consumed beverages in the world.

I believe that a lot of people fall in love with coffee, and I am one of them. However, coffee is hard on kidney when you already have Renal Failure. Some patients with Renal Failure strictly follow it. And some people may oppose to it. This is an old argument. Why do I say coffee is bad for patients with Renal Failure? There are three reasons as follow.

Ⅰ Coffee contains much caffeine, which is common sense. Many patients with Renal Failure maintain that caffeine has not bad effect on kidney disease, but we should not forget that coffee can always let spirit rouse, and then difficultly in falling asleep. Low quality of sleep and body can not get well rest, which may arouse the relapse of kidney disease.

Ⅱ Coffee restrains the absorption of ferrum, which is reported by dietitian. Patients with Renal Failure may know there will be renal anemia when Chronic Kidney Disease (CKD) develops into stage 3. At this moment, coffee plays a role in stopping the absorption of ferrum, which is bad for treating renal anemia
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The Confusion of a Patient with Renal Failure

Here is a message from a patient with Renal Failure, in which she expressed the confusion about her medical conditions.

Hi doctor, my creatinine clearance was 17.26ml/mins, my 24 hour urinary protein was 342 and the machine value was 21.6, but I have no symptoms of a kidney failure person, like blood in urine, swelling of feet and shortness of breathe. I want to know why and I wonder where I stand.

From what she said, we can feel that she is very surprised about the severity of her disease and confused why she did not present some symptoms of Renal Failure. Actually, many patients have the similar experience that no obvious symptoms attract their attention, but it has been at the late stages of Renal Failure when it is diagnosed.

Renal compensation

The kidneys in the body boast a great compensation. Even if we lost one kidney, we still can feel normally. Only when more than half function of kidney fails emerge the obvious symptoms. The common urine test includes creatinine, ptrotein and blood in urine. The patients usually never know about creatinine clearance test or GFR (glomeruli filtration rate). GFR is the best one reflecting the function of kidney and even more precise than the value of clearance creatinine test.

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Stage-4 Chronic Kidney Disease and Kidney Failure

More and more patients are diagnosed with Chronic Kidney Disease because of the poor living habits. Chronic Kidney Disease is divided into five stages according to Glomerular Filtration Rate (GFR). The decrease of Glomerular Filtration Rate is closely related to the declining of kidney function. Stage-4 Chronic Kidney Disease means patients have entered into the stage of Kidney Failure. GFR in stage-4 CKD is 15-29 ml/min. Stage-4 Chronic Kidney Disease can be seen a Kidney Failure. Patients with Kidney Failure should treat disease as soon as possible. Some patients are diagnosed with stage-4 Chronic Kidney Disease when they saw a doctor for the first time. They feel confused that before they go to see a doctor, there are no uncomfortable feelings or symptoms.

Do you know the compensatory ability of kidneys?

The kidneys are a pair of bean-shaped organs that lie on either side of the spine in the lower middle of the back. Each kidney weighs about ¼ pound and contains approximately one million to two million filtering units called nephrons. Each nephron is made of a glomerulus and a kidney tubule. The glomerulus is a miniature filtering or sieving device while the tubule is a tiny tube like structure attached to the glomerulus.

Compensatory ability of kidneys means 50% kidney function is enough for the normal work of the whole body. Normal people can give one kidney to another people. Generally speaking, if patients’ kidney function is damaged slightly or less than 50% percent, there are usually no symptoms so that people will ignore the existence of kidney disease. Therefore, people should take routine tests so as to guarantee the healthy body. As for patients with stage-4 CKD, they have already in a serious condition so there are many symptoms.

Do you know the symptoms of stage-4 Chronic Kidney Disease?

◆ Fatigue: Feeling tired is common for people with CKD and is often caused by anemia.

◆ Swelling: A person may notice swelling (edema) in their lower legs, hands or face around the eyes. With too much fluid, someone could even feel short of breath.

◆ Urination changes: Urine may be foamy if there is protein in it, or dark orange, brown, tea colored or red if it contains blood.

◆ Sleep problems: Some people have trouble falling asleep or staying asleep. Itching, muscle cramps or restless legs can keep them awake.

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Symptoms for Kidney Failure in Different Stages

Kidney Failure is usually divided into there stages, which are early-stage Kidney Failure, moderate-stage of Kidney Failure and end-stage Kidney Failure. Each stage has different characteristics. Some people want to know the knowledge about symptoms at each stage so as to judge at which stage Kidney Failure they are. Only according to the knowledge about symptoms, of course, can’t exactly or precisely know the specific stage of Kidney Failure. You should do urine test, blood test, kidney function test as well as bilateral Ultrasound, which can tell you the real illness condition scientifically.

Early-stage Kidney Failure

During this stage, patients are suffering from hypertension, ischemia, sepsis or nephrotoxin, and all of which can easily cause Acute Tubular Necrosis. However, no serious damages have been caused to kidney parenchyma during this time, so the symptoms are inconspicuous. In order to prevent the occurrence of Acute Tubular Necrosis, urine ordinary test and blood test are necessary for the timely detection and treatment of this disease.

Moderate-stage Kidney Failure

Vomiting and Nausea of Patients with Kidney Failure

Most patients with Kidney Failure have symptoms of nausea and vomiting which are usually considered as stomach trouble, delaying treatment. Most Patients with Kidney Failure are confused that why they have the symptoms of nausea and vomiting.

When patients are suffering from end-stage kidney failure, body metabolism can be changed, which can stimulate bacteria lived in gastrointestinal tract to secrete urea enzymes. This urea enzyme can break urine down into amino which has a strong stimulation to gastrointestinal tract, causing symptoms of nausea, vomiting, low appetite and hemorrhage of ulcer, or even intractable hiccup. Bad smell in mouth and amino smell in breath happen complicatedly. Besides, diarrhea is also a serious symptom of Patients with Kidney Failure.

Urea nitrogen is the main toxin of patient with kidney failure, but not the only one. Some other toxins are also related with kidney failure, such as guanidines, phenols, aromatic acids, creatinine, uric acids and fatty acid, accumulation of all these toxins can cause gastrointestinal tract symptoms and affect permeability of cell membrane and ion operation. Besides, this can also damage Red Blood Cells, which can lead to Anemia. Most of these toxins can be degraded in kidneys, but when Kidney Disease develops into end stage, kidney clearance rate decreases obviously. For this reason, there is a high concentration of these toxins in blood, and then clinical symptoms of vomiting, diarrhea and other symptoms happen.

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The Early Signs of Uremia

Uremia is the end stage of Renal Failure. It is a long time from Kidney Diseases to Uremia. Some people with kidney diseases are surprised at the news that they have been at the stage of Uremia, because they feel nothing bad in daily life. Actually, it is they that neglect the early signs of Uremia, which usually undermine their health covertly. There are four main signs indicating Uremia.

Pale Face People with anemia usually look pale. The same goes to patients with Uremia, because those patients always have renal anemia. At the stage of Uremia, metabolic wastes depositing in body and electrolytes are put in disturbance, which restrain the producing and maturing of red blood cells. As renal anemia developing slowly, people usually treat it as the common anemia and have no ideal to test their renal functions, which delays or miss the best chance of treatment.

Swelling Swelling is an obvious sign for being found, but it is also easily to be ignored. At the beginning, swelling only occurs to eyelid in the morning and will fades away after noon. When people feel tired, swelling will happen to feet and disappear after they have a rest, which seldom attracts their attention. It is late to find Generaldropsy, when the disease has developed into Uremia.

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Cold Limbs for Patients with Kidney Failure

If you or your relative have kidney disease, especially for patients at the stage of Kidney Failure, you may curious about the symptom of cold limbs. The symptom of cold limbs is common for patients with Kidney Failure. Cold limb is caused by Kidney Failure so that in order to relieve cold limbs, we should start from the treatment of Kidney Failure. Only when Kidney Failure is cured, can the symptom of cold limbs can be treated.

The cause of cold limbs:

Patients with Kidney Failure mean kidney insufficiency, which will lead to a series of symptoms such as edema, anemia, cold, vomit and nausea and so on. Most of the symptoms are caused by blocked blood circulation, which will lead to ischemia and nausea. In case ischemia and anoxia occur, the whole body system will be affected. Immune complex in blood vessels will make artery diameter narrow down, blood backflow ability decreased and then peripheral circulation decreased. If blood circulation is improved, the symptoms of ischemia and anoxia in kidneys can be improved, which means kidney can, to some extent, recover the function of discharging kidney wastes and providing enough cleaning blood to each organ, thus the symptom of cold limb can be improved.

How to recover kidney function?

Micro-Chinese Medicine Osmotherapy has the function of dilating blood vessels, anti-inflammation, anti-coagulation and degrading immune complex and then preventing kidney fibrosis. These functions taking effect at the same time can repair damaged kidney tissues.

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Symptoms of Stage 4 Chronic Kidney Failure

For the stage standards are various in different district, I will introduce the damage according to international standard, and Chronic Kidney Disease is divided into five stages. This standard is divided according to glomerular filtration rate (GFR): the first stage is≤90ml/min; the second stage is 89ml/min～60ml/min;the third stage is 59ml/min～30ml/min;the fourth stage is 30ml/min～15ml/min;the fifth stage is≤15ml/min. Actually all five stages are the process of deteriorating into Chronic Kidney Failure. The stage 4 Chronic Kidney Disease can be called Chronic Kidney Failure.
Chronic Kidney Failure is a long-term disease and caused by various pathogenesis. The pathological mechanism is: metabolic wastes can not be discharged out of body and then pile up in human body, which is just like toxicants piling up in human body. Long-time accumulation of metabolic wastes can lead to kidney fibrosis, and then kidney will lose its functions of filtrating blood and discharging metabolic wastes so the kidneys can not producing urine or have little urine. Kidney dysfunction makes the metabolic wastes such as urea nitrogen and Creatinine can not be discharged out of human body. These harmful substances can flow to each body part along with blood and then damage each body system.
Digestive Tract System
If they enter into digestive tract, gastrointestinal mucosa will be stimulated so that symptoms such as nausea, vomit and diarrhea occur. Oral mucosa will also have fester and there will be the smell of ammonia in patients' mouth.
Respiratory Tract System
If these wastes enter into respiratory tract, there may be uremic bronchitis, pleuritis and pneumonia. After the pericardium is stimulated by urea, it can cause uremic pericarditis.
If the wastes are discharged out of body from sweat gland, patients' skin will have uremic frost.
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Chronic Renal Failure and Muscle Twitch

Patients with early-stage Chronic Renal Failure should get treatment timely so as to prevent the deterioration of disease. Long-time Chronic Renal Failure will lead to serious damage to human body. There are some symptoms such as hypocalcemia, hyperphosphatemia and electrolyte disorder, which can cause muscle pain.
1. Hypocalcaemia
The Cause of Hypocalcaemia:
Patients with Chronic Renal Failure usually have inappetence, vomit, nausea and diarrhea, which can lead to insufficiency of calcium. At the same time, the damage of digestive tract will influence the absorption of calcium. Most calcium is discharged out of human body through urine. This is the main reason for patients with Chronic Renal Failure to cause Hypocalcaemia.
The damage to muscles from Hypocalcaemia:
The most obvious symptom coming from Hypocalcaemia is excessive excitability of nerves and muscles. Calcium Ion has the ability to restrain internal flow of Sodion. When people with Hypocalcaemia, the inhibitory ability decreased, this can lead to decreased threshold of action potential. The repeating stimulations can lead to exciting nerves and muscles such as muscle pain or muscle twitch. Slight Hypocalcaemia usually manifest with finger and toes pain, arms and legs numb or twitch, stabbing pain; when calcium loses more, there will occur tetany; more serious condition can have whole body skeleton spasm and smooth muscle spasm, and respiratory tract can have bronchospasm or even apnea; vasospasm can show headache, angina and Reynolds.
2. Hyperphosphatemia
The cause of Hyperphosphatemia:
When the kidneys are damaged, the glomerular filtration rate will decrease so that the redundant wastes such as phosphorus, serum creatinine and BUN can not be discharged out of human body. As for phosphorus, long-time accumulation in blood can lead to Hyperphosphatemia. Balanced calcium and phosphorus can promote the use of inorganic salt. Silicate can keep the metabolism of Vitamin D and then maintain homeostasis of calcium. High phosphorus can influence the absorption of calcium.
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