The Dilemma of Kidney Transplantation in China

The Dilemma of Kidney Transplantation in China

Recently, a young man has attracted the attention of many Chinese people. This young man, called Liu Fei, has being suffering from the End Stage Renal Failure for one year. His mother’s kidney is suitable to him for transplantation, but his mother refused and left home, which provokes a heated discussion among Chinese people.

Liu Fei was born in a poor family in Sichuan province. Their life mainly depends on the money made by his parents in taking part time jobs. When he was diagnosed as the End Stage Renal Failure, he left school and leased a tricycle to make money for dialysis. In China, there are many people without medical care in some poor areas, which means that some treatments are usually unaffordable to them, such as dialysis and kidney transplantation. The problem of kidney transplantation lies not only in the shortage of money but also in the limited kidney source. Chinese people who are unwilling to donating their kidney is not the persons without loving hearts but they owning a traditional thought that they must have a intact body to rebirth after their death and their children consider it is an important filial piety to keep their parents in whole bodies. In addition, many people hesitate to donate their kidneys because they think it is harmful to their health and may make them lose the ability of working.

Condemned by so many people, the mother of Liu Fei expressed her thought that if she donates her kidney to her son, there will be two patients in this poor family and they can not afford the medical fee after transplantation. Maybe this mother indeed has no choice but to make money and wait for another suitable kidney towards her son, or maybe she is scared to take the responsibility as a mother, but it is really a dilemma in China among patients with the End Stage Renal Failure. Besides complaining the underdeveloped economic conditions, what else can we do? Is there really no other choice for those patients apart from kidney transplantation and dialysis?

Actually, according to each patient’s medical conditions, as long as their surviving nephrons are in protection and the damaged nephrons can be recovered enough or even partially, there is a chance for them to get rid of dialysis, prolong their lives and even need not to receive kidney transplantation.

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What Can We Do Excepting Waiting for Kidney Sources?

This is a message from internet, which makes me think a lot.
I am a woman from Suriname, I am 27 years old and I have taken kidney dialysis three times a week since last year. I really don't like it at all. My mom’s life ended while starting the therapy. I can not do anything that I liked to do. I am sad but I don't give up hope, day after day I am fighting. I have a lot of questions. What can I do to get a kidney transplant? In my country (Suriname) they don't do transplantations. Please help me contact others to help me, with finding information about transplanting kidneys or people who have had transplantation.
Many patients with Renal Failure have no choice but dialysis. Kidney Transplantation is destined to be adopted when the disease deteriorated in to the end stage. It is common that they tend to search the matching kidneys in advance. Once we suffer from Chronic Renal Failure, what can we do except waiting for Kidney source?
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Lower Serum Creatinine from the Root

High Serum Creatinine is caused by the declining of kidney function. Serum Creatinine should have been discharged out of body through urine. However, the declining of kidney function can lead to oliguria so that extra metabolic wastes such as Creatinine, blood urea nitrogen and potassium and so on will be accumulated in blood. In order to lower Serum Creatinine, we should use treatment method to recover kidney function and improve glomerular filtration rate so as to increasing the ability to discharge toxins such as Creatinine out of body.
People with high Serum Creatinine should take dialysis which can eliminate toxins in blood. However, people should know that dialysis is not a treatment method which means dialysis can only eliminate toxins and relieve uncomfortable feelings temporarily. I addition, western medicines used to lower Serum Creatinine also can only lower Serum Creatinine temporarily. People should use therapy which can lower Creatinine from the root and then high Creatinine will not relapse.
Combined use of Micro-Chinese Medicine Osmotherapy and Stem Cell Transplant can lower Serum Creatinine from the root with following steps:
1. Blocking kidney fibrosis. Micro-Chinese Medicine Osmotherapy can degrade scar tissues and immune complex so as to discharge them out of body. These scar tissues and immune complex can secrete inflammatory cells, which will further damage kidney function so we should eliminate them so as to avoid the further damage of kidney tissues.
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An American with Nephrotic Syndrome is under Treatment in Our Hospital

Name: Michael

Nationality: America

Gender: Male

Age: 33

Diagnosis: Nephrotic Syndrome

Michael’s disease condition:

On September 6th, 2009, Michael was suggested having a rest by his doctor for edema occurred in his low body part. He thought this is caused by overstrain, and then he followed his doctor’s advice and took a rest for one month but his edema condition is more serious. Michael decided to check up carefully so as to find the exact reason so he took renal biopsy, blood test and urine test, however, the doctor find nothing. At that time his Creatinine is 108ml/min. Several months later, he felt more uncomfortable and then he went to take renal biopsy again. This time he was diagnosed with Focal Segmental Glomerular Fibrosis (FSGF). In later days more symptoms occurred such as proteinuria, hypertension and anemia. In 2010, the edema conditions relapsed five times. The western medicines can not thoroughly eliminate his edema condition.

Michael came to Shijiazhuang Kidney Disease Hospital, China:

On July 12th, 2011, Michael came to our hospital. He was diagnosed with Nephrotic Syndrome and his disease was caused by Focal Segmental Glomerulosclerosis (FSGS) and Renal Anemia as well as Renal Hypertension. Michael had serious edema and his two arms were lifted by his bulged body. He can’t walk for his feet had serious edema. His skin looked like transparent and we can see the capillaries clearly, which is caused by severe edema. His Creatinine is 356ml/min on July 12th.

Micro-Chinese Medicine Osmotherapy Deals with Creatnine and Edema

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Can Kidney Diseases be Treated

Many patients with kidney disease ask to what degree our hospital can treat their disease. It depends on the repairing degree of the five intrinsic cells.

We study all kinds of kidney diseases according to the five intrinsic cells. Each kidney disease belongs to a specific type of intrinsic cells. They are Glomerular Epithelial Cells, Glomerular Endothelial cells, Glomerular Mesangial Cells, Kidney Tubulus Epithelial Cells and Mesenchymal Fibroblast. Long-time damage of five intrinsic cells will lead to renal fibrosis, which is the origin to cause all kidney diseases. If we take measures to recover the five intrinsic cells we can get rid of kidney disease completely. Usually inflammation and infection are the reason to cause renal fibrosis. Some other patients with complications such as Diabetes, Hypertension or hepatitis B can also lead to renal fibrosis.

In order to block the damage of renal fibrosis, first we need to expand blood vessels so as to relieve the symptoms like ischemia and anoxia which are caused by inflammatory pathological damage. Second we need inflammatory treatment to block its damage to kidney. Third, we should eliminate the rubbish in kidney which means avoiding forming thrombus, and then keeping regular blood circulation. Fourth, degrade fibrous tissues ECM, only after we degrade all the ECM, can the disease condition reverse and repair the kidney completely.

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Why People Choose Micro-Chinese Medicine Osmotherapy

Before we answer the question, we should the know what the most important thing to patients of Renal Failure is. It is the curative effects that all patients of Renal Failure are seeking for. Therefore, we can make a conclusion about the reason for people choose Micro-Chinese Medicine Osmotherapy is that the Osmotherapy has an effective effects in treating Renal Failure. In order to give you an clear explanation, the brief introduction, principle and functions will be introduced here.

Introduction of Micro-Chinese Medicine

Micro-Chinese Medicine is neither an oral medicine nor operation, it is the medicine absorbed through skin by osmoscope. The medicine is processed by the processing technology which can microniz the Chinese medicine molecules of micro-sized diameter into one thousandth smaller granules by using ultrasonic cavitations, and then make the effective ingredients of the Chinese medicine overflow fully.

Principles of Micro-Chinese Medicine Osmotherapy

1. Activating remaining renal inherent cells and helping recover the metabolism

Generally speaking, there are three kinds of cells in kidneys: necrotic cells, damaged cells and the remaining healthy ones. The Micro-Chinese Medicine can recover the function of the damaged cells, thus activating the lost renal functions.

2. Improving the micro-circulation and creating repairing environment

Micro-Chinese Medicine can expand blood vessels, keep blood circulation, adjust blood pressure, improve the micro-circulation and relieve the problems of ischemia and anoxia, thus creating a favorable environment of repairing as well as lightening intoxication.

3. Two-phase immune adjustment and metabolism

The Micro-Chinese Medicine can enhance the lymphocyte transform rate, thus enhancing the sterilizing ability of the patients with Renal Failure so as to establish the repairing basis.

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Multi-Targeting Function of Micro-Chinese Medicine Osmotherapy for Repairing Damaged Renal Intrinsic Cells

1. Activate the function of the remaining renal intrinsic cells, reverse and recover cell metabolism.
(1) Activate the metabolic function of renal intrinsic cells and speed up the reconstruction of glomerular function.
(2) Protect endothelial cells, prevent further damage and reverse the damaged endothelial function.
(3) Activate the self-repair mechanisms of renal intrinsic cells.
2. Improve microcirculation of the damaged kidneys, provide aerobic repairing environment and accelerate repair of cells and reconstruction of kidney units.
Whether the damaged kidneys can be successfully repaired or not depends on the kidney microcirculation state and aerobic repairing environment. If the root of renal fibrosis—ischemia and hypoxia can not be restrained, damaged kidneys surely can not be repaired. Therefore, in order to effectively recover the damaged kidneys, we must improve the ischemia and hypoxia environment.
3. Improve the internal environment of damaged kidneys, alleviate toxic symptom and provide a favorable environment for repair and reconstruction.
(1) Through oxygen supply, it can increase aerobic metabolism, promote EPO secretion, improve anemia and suppress the formation of renal fibrosis.
(2) Through the targeting function of vasodilation, it can increase effective blood circulation, improve local ischemia and hypoxia as well as repair the damaged epithelial cells of renal tubule and recover their function.
4. Regulate immunity and metabolic function, control the progress of disease and provide a foundation for repair and reconstruction.
(1) Strengthen percent conversion of lymphocyte in patients, increase absorption to IL_2, enhance the activity of killer cells and promote cellular immune function.
(2) Micro-Chinese Medicine can restrain the reaction from mesangial cells and neutrophil to active oxygen, damage of inflammatory factors TNF-αand PDGF to vascular endothelial cells.
(3) Strengthen the phagocytic activity of immune cells in patients with a low immunity, speed up phagocytosion to apoptotic cells and immune complex, thus laying foundations for purifying internal environment.
(4) Activate IgG and IgM and strengthen immunity of body fluid.
5. Provide repairing materials for recovery and repair.
(1) Micro-Chinese Medicine contains more than ten trace elements, especially zinc and selenium, which can promote synthesis of protein and enzyme and strengthen immunity.
(2) Active substances in Chinese medicine are rich in various vitamins and organic acid.
(3) Promote DNA replication in cells and accelerate synthesis of protein which will involve in renal recovery.
(4) Active substances in Chinese medicine are rich in multiple essential amino-acid which can provide nutrition for the repaired cells.Multi-Targeting Function of Micro-Chinese Medicine Osmotherapy for Repairing Damaged Renal Intrinsic Cells

Clinical Treatment Effect of Active Substances in Micro-Chinese Medicine on Blocking Renal Fibrosis (Ⅰ)

Short-Term Clinical Treatment Effects of Vasodilatory Function of Active Substances in Micro-Chinese Medicine
1. Blocking treatment method:
Dilating blood vessels function of Micro-Chinese Medicine can increase effective blood perfusion for the damaged renal intrinsic cells, improve effective blood circulation of damaged renal intrinsic cells, relieve ischemia and hypoxia state and block the startup factors of renal fibrosis.
2. Clinical treatment effect:
If the above treatment method is properly carried out, it will generate the following treatment effect recently:
(1) Short term treatment effect in clinical, when glomerular filtration improves:
① Urine volume gradually increases;
② Ammonia smell in urine gradually becomes thick;
③ The color of urine will gradually turns dark;
④ Creatinine excreted with urine in 24 hours gradually increases.
(2) Short term manifestations in clinical, when the state of high blood pressure and high filtration has been improved:
① Proteinuria and blood urine decline little by little;
② Protein in 24 hours will gradually reduces;
③ Glomerular Filtration Rate (GFR) gradually improves;
(3) Recent treatment effect, when various functions of renal tubular promote:
① When resorption function of renal tubular improves, renal glycosuria will lessen or disappear. When taking qualitative or quantitative check, it is found that urine protein will gradually decline;
② When regulatory function of renal tubular improves, the state of electrolyte disturbance in blood will gradually improve as well as acid-base imbalance, symptom of acid-base poisoning completely disappear;
③ When concentration function of renal function improves, symptom of increased nocturia lightens, symptom of low urinary specific gravity in the morning improves and specific gravity restores to more than 1.025.
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Treat Kidney Failure with Micro-Chinese Medicine Osmotherapy

How about treating Kidney Failure by Traditional Chinese Medicine? The treatment effect of Traditional Chinese Medicine is slow but very effective. Experts suggest choosing TCM treatment method “Micro-Chinese Medicine Osmotherapy”.
1. Vasodilator Effect of Micro-Chinese Medicine Osmotherapy

For kidney disease patients, due to inflammatory mediators and various oxidative stress reactions in the blood, vascular tissue at all levels will be damaged, which will definitely lead to bad blood circulation and microcirculatory system ischemia and anoxia. Then the renal intrinsic cells will appear ischemia and anoxia, which can cause damage to kidneys. Micro-Chinese Medicine Osmotherapy can dilate all levels of artery in the kidneys as well as the whole body, and relieve the high blood pressure and the tension state of the vessels, thus improve the state of renal ischemia and hypoxia and restrain the origin of renal fibrosis.
2. Anti-inflammatory Effect of Micro-Chinese Medicine Osmotherapy
A large amount of inflammatory factors and renal toxic factors will accelerate the process of Renal Fibrosis and damage to renal intrinsic cell. Micro-Chinese Medicine Osmotherapy can solve all kinds of inflammatory reaction caused by this and suppress the further damage of renal intrinsic cells.
3. Anti-coagulation Effect of Micro-Chinese Medicine Osmotherapy
The appearance of inflammatory lesions will inevitably strengthen the activity of platelet. The increased platelet will definitely result in the increase of the blood viscosity, causing clotting. The increase of blood coagulation factors will gradually lead to the formation of different degrees of thrombus, which will give rise to microcirculation blocking and ischemia and anoxia. Micro-Chinese Medicine Osmotherapy has anti-coagulation effect, which can prevent the formation of thrombus and promote the repair of renal intrinsic cells.
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