Symptoms of Stage 4 Chronic Kidney Failure

For the stage standards are various in different district, I will introduce the damage according to international standard, and Chronic Kidney Disease is divided into five stages. This standard is divided according to glomerular filtration rate (GFR): the first stage is≤90ml/min; the second stage is 89ml/min～60ml/min;the third stage is 59ml/min～30ml/min;the fourth stage is 30ml/min～15ml/min;the fifth stage is≤15ml/min. Actually all five stages are the process of deteriorating into Chronic Kidney Failure. The stage 4 Chronic Kidney Disease can be called Chronic Kidney Failure.
Chronic Kidney Failure is a long-term disease and caused by various pathogenesis. The pathological mechanism is: metabolic wastes can not be discharged out of body and then pile up in human body, which is just like toxicants piling up in human body. Long-time accumulation of metabolic wastes can lead to kidney fibrosis, and then kidney will lose its functions of filtrating blood and discharging metabolic wastes so the kidneys can not producing urine or have little urine. Kidney dysfunction makes the metabolic wastes such as urea nitrogen and Creatinine can not be discharged out of human body. These harmful substances can flow to each body part along with blood and then damage each body system.
Digestive Tract System
If they enter into digestive tract, gastrointestinal mucosa will be stimulated so that symptoms such as nausea, vomit and diarrhea occur. Oral mucosa will also have fester and there will be the smell of ammonia in patients' mouth.
Respiratory Tract System
If these wastes enter into respiratory tract, there may be uremic bronchitis, pleuritis and pneumonia. After the pericardium is stimulated by urea, it can cause uremic pericarditis.
If the wastes are discharged out of body from sweat gland, patients' skin will have uremic frost.
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