2012/12/24

Micro-Chinese Medicine Osmotherapy Cure Mesangial Proliferative Glomerular Nephritis


Mesangial Proliferative Glomerular Nephritis is a disease that affects the glomeruli in the kidneys. Most instances of MPGN are caused by other diseases or disorders, including autoimmune diseases, chronic infections, monoclonal immunoglobulin deposition diseases, and hereditary diseases. The idiopathic type of MPGN is seen more commonly in persons aged 8-30. There is a new treatment in our hospital, which is good news for MPGN patients. It is called Micro-Chinese Medicine Osmotherapy. Here I would like to give you a brief introduction of Micro-Chinese Medicine Osmotherapy.
What is Micro-Chinese Medicine?
You may have heard of Chinese medicine (Chinese herbs) before. Here only a simple different that is 'Micro-' has been added, but the means of it have changed greatly. Let me introduce for you in detail.
How dose Micro-Chinese Medicine work in the body?
The root pathological change of kidney disease lies in the fibrosis of renal functional cells. Only when the fibrosis is blocked, can deterioration of kidney disease be stopped. Study shows that fibrosis results from the insufficiency of blood and oxygen in the kidneys. Rightly, Micro-Chinese Medicine has good curative effect to improve the state of lacking blood and oxygen. Specifically speaking, Micro-Chinese Medicine can dilate blood vessels and decrease blood coagulation, thus improving blood circulation of kidneys. In addition, it can also decrease inflammatory reaction and degrade extracellular matrixes (ECM) both of which contribute to fibrosis of renal functional cells. In this way, Micro-Chinese Medicine can effectively prevent fibrosis and thereby stop kidney disease from progressing.

2012/12/07

Symptoms for Renal Failure


Kidney is as important as the garbage disposal to a city which is actually responsible for purifying blood and filtrating metabolic wastes. The city will be disorder and ruined if the garbage disposal has been destroyed. Therefore, life would fail if kidneys fail. To some degree, prevention is better than cure, so it is necessary for people to know more about Renal Failure. Various common symptoms of Renal Failure will be introduced in this article.
1. Changes in Urination
Most patients of Renal Failure has changes in urination. People may notice that urine may be foamy or bubbly. Some people may urinate more often than the usual. While some may urinate less often, or in smaller amounts than usual. Some times patients may also have to apply pressure while urinating. High levels of urea in blood can result in vomiting and/or diarrhea, dehydration nausea, weight loss, nocturnal urination, blood in urine and so on. There are still some people have symptoms like more frequent with pale urine or less frequent but dark coloured urine.
2.Edema
Edema or swelling may occur in legs, ankles, feet, face or hands. For some children ,it is usually a suffering. Many children with edema will have a moon-shape face, which brings pain to them in both physic and mind.
Other symptoms may be like Fatigue, Skin Rash or Itching, Metallic Taste in Mouth or Ammonia
3. Anemia
Healthy kidneys produce the hormone erythropoietin which stimulates the bone marrow to make oxygen-carrying red blood cells. As the kidneys fail, they produce less erythropoietin, resulting in decreased production of red blood cells to replace the natural breakdown of old red blood cells. As a result, the blood carries less hemoglobin, a condition known as anemia. This can result in feeling tired or weak, memory problems, difficulty concentrating, dizziness and low blood pressure.
4. Other Symptoms
Breath, Nausea and Vomiting, Shortness of Breath, Feeling Cold, Dizziness and Trouble Concentrating, Leg or flank pain may happen to patients of Renal Failure. These are actually the usual symptoms. Even if the symptoms are minor or does not have any longer impact should be brought into the notice as earlier as possible.

2012/10/17

How to treat protein in urine


The normal 24-hour protein in urine range ≦ 0.15g, routine laboratory testing was negative.Such as urine protein> 150 mg / day, urinary protein, the human body from the urinary protein content increased significantly, and are abnormal urinary protein. Urine protein isgenerally not too serious, you are sick is not very understanding, control and treatment ofsuch patients need timely. A long period of urine protein renal inherent cell structure isdamaged, leading to kidney filtration barrier injury, can not stop resulting from theleakage of protein. Treatment only symptomatic treatment rather than the reasons fortreatment for the inherent cell structure caused by kidney damage, protein is only temporary control, easily repeated. The root cause of treatment should be inherent in thekidney cells.
How to treat protein in urine
Can be drawn from the above, the treatment of urinary protein the correct treatment is thetreatment of kidney. Kidney Disease hospital of micro-penetrationtherapy of Chinese medicine to start first from the perspective of immunology, issuedaccording to the human body tissues and organs of the holographic theory of biology,physiology, pathology information and drug action information, the overall concepts anduse of traditional Chinese medicine diagnosis and treatment methods combined with theintroduction of high-tech renal detection of ECT by U.S. Sunoco, accurate selection of kidney disease hospital developed a series of traditional Chinese medicine preparation, the use of holographic instrument kidney area iontophoresis. With the oral medicine at the same time, activate the body’s immune system, re-regulate the immune function enables the body to produce huge super-self-repair capacity, accelerate its metabolismand repair, the new health and blood stasis, regulating yin and yang, improving renal pathological changes, clear the destructive substances in the kidney (immune complexesand metabolites), the stability of residual renal function; protect cell membranes, andscavenge oxygen free radicals, thereby protecting the residual renal units, and are destroying the renal unit to recover from the fundamental, atrophy of the kidneys to improve, so that patients with renal failure to avoid, delay, or to get rid of the dialysis to achieve the restoration and preservation of residual renal function ultimately to fundamentally eliminate the urine protein, red blood cells (occult blood) in urine, so as to achieve the purpose of treatment.

2012/08/22

Renal failure and High creatinine


People suffering from Renal Failure or some kind of kidney diseases would probably experience high creatinine levels. As a byproduct of creatine, it is produced through muscle metabolism and usually be filtered through kidneys. Due to the specific features of creatinine, it is often used for judging the kidney function. Elevatedcreatinine levels may indicate the kidney problems and requires immediate treatments.
Symptoms of high creatinine
Some individuals may find out they have Renal Failure when there is extremely high levels of creatinine in routine blood tests, without feeling any symptoms at all. In other cases, patients may suffer from problems, such as felling tired or weakness, dehydration, confusion, shortness of breath, etc.
The most common causes of longstanding kidney disease in adults are high blood pressure and Diabetes Mellitus. High serum creatinine may also be caused by ingestion of large amount of dietary meat. Other reasons may also cause high serum creatinine, which can be seen as follows:
1. Dehydration can lead to elevated creatinine by causing blood fluid concentration and reduction of kidney blood flow.
2. Nephrotoxic medicines taken by those with kidney diseases can lead to elevated creatinine, which can be irreversible.
3. Over fatigue may lead to intermittent high serum creatinine.

2012/08/16

Dialysis in Diabetic Nephropathy: Pros and Cons

Cons and Pros for dialysis treatment in Diabetic nephropathy? End-stage diabetic nephropathy patients undergoing have two choices of dialysis: long-term hemodialysis and continuous ambulatory peritoneal dialysis. Recently, the vast majority of patients with end-stage diabetic nephropathy to take peritoneal dialysis, because it does not increase the heart load and stress, better control of extracellular fluid volume and hypertension. Also by intraperitoneal injection of insulin, easy to operate, cost savings, but some patients due to long-term peritoneal dialysis absorb a large number of glucose Erzhi obesity and high cholesterolDiabetic with ESRD, which type of dialysis to choose?Patients with diabetic nephropathy to advanced prone to serious deterioration of renal function, and even uremia. Although dialysis treatment is not advanced diabetic nephropathy in patients with the best treatment, but if early, long-term dialysis treatment can greatly improve the survival rate of patients. When serum creatinine in the 350-440umol / L should be prepared to vascular pathways; when serum creatinine reached 600umol / L or more, you can start dialysis treatment. Clinical in the end is to choose hemodialysis or peritoneal dialysis should be selected according to the disease and the specific conditions.Hemodialysis.In diabetic nephropathy patients on long-term hemodialysis patients, 1-year survival rate of more than 80%. Older, serious condition acceptable to the dialysis treatment. Dialysis in advance, less uremic complications; where the pre-dialysis and dialysis process, better control of blood pressure, attention to fluid balance, to ensure a reasonable nutrition, the survival rate of patients will improve. Hemodialysis process can also be some problems, such as poor vascular pathways, large fluctuations in blood pressure, worsening retinopathy and even blindness and a variety of cardiovascular complications.

[Peritoneal dialysis]1-year survival rate of peritoneal dialysis in diabetic nephropathy was 80% to 90%. Its main advantages are:① cardiovascular system is more stable, better blood pressure control.② to avoid the path of blood vessels.(3) through the abdomen, and injection of insulin, blood sugar control better.The retinopathy can be stable improvement.(5) PD operation is more convenient to patients themselves.⑥ in the high molecular substances cleared.Its shortcomings: 1-prone abdominal infection after infection, easy to shadow noon dialysis effect.The peritoneal dialysis daily loss of protein l0g to pay attention to protein intake.In summary, can not be advanced diabetic nephropathy in kidney transplant ambulatory continuous peritoneal dialysis results better than hemodialysis.  

Considering  peritoneal dialysis, dialysate glucose was partially absorbed by hypertonic dialysate induced hyperosmolar coma, so pay attention to the use of insulin dose adjustment, while avoiding hypoglycemia. However, the possibility of peritonitis in peritoneal dialysis when compared with non-diabetic patients, should pay close attention to actively prevent infection. Dialysis costs are high, the patient's body is even more painful. Is there a treatment more effective and more to reduce the suffering of the patient? 
The answer is yes. after painstaking research, the original micro-based traditional Chinese medicine penetration therapy.
 Related article:
How do Diabetics with High Creatinine Keep away from Dialysis

Is Dialysis only Choice When Creatinine is High in Diabetics

In recent years,incidence of Diabetes and hypertension increased significantly i coupled with the arrival of an aging society. The elderly renal function itself is a downward trend in the role of various etiologies, renal function is more easily damaged. Easy to overlook a lot of patients have symptoms of kidney disease before the knowledge of the kidneys and kidney disease, little is known about or nothing about, so that kidney disease has shown. Patients disapprove, of these symptoms is fatigue due to rest for some time will heal. There are still some patients, due to economic conditions, the disease can have a delaying tactics, less than a last resort not the hospital. Whether it is inadvertently overlooked, or the indifference of the disease, depicting disease in slow development of deterioration, and eventually developed into uremia uremia is a serious kidney disease, most doctors recommend dialysis, then, under what circumstances must do dialysis do?

  
 Indications to rapidly start dialysis in chronic renal failure:
    (1) drugs can not control the hyperkalemia ≥ 6.5mmol / L;

    
(2) sodium retention, oliguria, anuria, high degree of edema associated with heart failure, pulmonary edema, high blood pressure;

    
(3) metabolic acidosis pH <7.2;

    
(4) complicated by uremic pericarditis, gastrointestinal bleeding, central nervous system symptoms such as trance, drowsiness, coma, convulsions, and psychiatric symptoms.

    
Second, early dialysis indications: uremia progress quickly obvious deterioration in general condition, severe gastrointestinal symptoms, and can not eat, malnutrition; concurrent peripheral neuropathy; red blood cell volume in 15%; diabetic nephropathy, kidney disease of connective tissue disease, old age patients.

    
Third, the clinical manifestations of uremia, such as nausea, vomiting, edema, heart failure;

    
Above, serum creatinine> 707.2μmmol / L, and endogenous creatinine clearance <10ml/min; uremic nitrogen to 30mmol / L (80mg/d1)

    
In addition the experts advise patients to control blood sugar and blood fat,follow a  low-salt diet, limit protein intake, smoking cessation, avoid renal Poison, lifestyle changes, correction of anemia, correction of acidosis, the treatment of renal osteodystrophy, correcting malnutrition, treatment cardiovascular complications and so on. The doctor will accurately determine when to require dialysis treatment, ahead of a comprehensive pre-dialysis missionary. So be sure to actively cooperate with the doctors.

    You may also communicate with free experts online for more about it. 
Related article:
Dangers for Patients with Diabetic Nephropathy on Dialysis

2012/08/12

How to Reduce Creatinine Level for Patients with Polycystic Kidney Disease

Creatine is used as a source of energy by your muscles. According to MayoClinic.com, 95 percent of creatine in the body is located in your skeletal system. Too much creatine in your body can lead to muscle cramping or gastrointestinal symptoms such as stomach discomfort, diarrhea and nausea.
creatinine level is usually considered as one of the items that can reflect glomerular filtrating function.
In stage of Polycystic Kidney, cysts are still small and their pressure on kidney is also small. Besides, symptoms usually appear after pathological injury. So creatinine level is normal in this stage. But when creatinine begins to increase, it usually means that kidneys have already been injured.
When the kidneys cannot work efficiently, as with Polycystic Kidney Disease (PKD), creatinine levels may rise. How to lower creatinine effectively?
1. Vegetarian diet: By consuming a largely plant based diet you will be helping your body in a few distinct ways
- Dietary sources of creatine and creatinine are only found within animal products, therefore you will be reducing the burden of “extra” creatine and creatinine circulating through your blood by eating a largely plant based diet.
2. Avoid creatine supplements: not only do high doses of this large molecule cause kidney problems (because of its large size it can cause the kidneys to swell), but by supplying the body with extra creatine, you will cause more creatine to be spontaneously converted to the by-product creatinine.
3. Avoid strenuous physical activity: thereby decreasing the breakdown of creatine into creatinine.
4. Nettle leaf tea: drink 1 to 2 cups a day. Nettle leaf tea is a simple yet powerful kidney tonic that can improve kidney function and reduce serum creatinine levels. (Tip: Double check that it is the leaf and not the root, the leaf if for your kidneys, the root is for male prostate disorders)
5. Avoid the over consumption of Vanadium: Although very beneficial for the body, particularly for diabetes and blood sugar problems, over consumption of the mineral vanadium has been linked to increased blood creatinine levels (stay under 100mcg a day).

Cause Of High Creatinine Levels In Blood


The kidneys are primarily responsible for regulating the levels of creatinine in the blood and any factor that tends to interfere with normal functioning of the kidney can result in elevated levels of creatine in the blood. These factors include,
Kidney dysfunction caused due to azotemia or kidney failure is one of the primary cause of high creatinine levels
Kidney stones and recurrent urinary tract infections may also be responsible for elevated levels of creatinine
Hypertension and diabetes mellitus may also result in impaired kidney functions which in turn may result in elevated levels of serum creatinine
Certain drugs and medications are also responsible for transit rise in the creatinine levels
Consumption of large amount of dietary meat may also result in elevated levels of creatinine which is often transient
Malnutrition may result in excessive breakdown of proteins in the body, which in turn would result in elevated levels of creatinine levels

How to reduce creatinine naturally


Creatinine is a very important source of energy for our body. Obtained from foods and other supplements available from health food stores, creatinine is used by the body to increase levels of energy and the mass of muscles.
However, for cases of over-intake of creatinine supplements may lead to a great increase in its levels in our body. In this case, a person with high creatinine is at great risk to heart and kidney damage, dehydration, and in worst cases, death.
Too much creatine in your body can lead to muscle cramping or gastrointestinal symptoms such as stomach discomfort, diarrhea and nausea. Decreasing creatine can help alleviate these symptoms.
Step 1
Visit your physician. Your physician can run tests and find out if you have creatine allergies or other conditions that require a decrease in creatine levels.
Step 2
Avoid supplementing creatine. Creatine is often used by athletes to improve muscle building and to raises energy during workouts. If you currently take creatine supplements, gradually reduce your intake to give your body time to adapt and return to normal levels.
Step 3
Cut down on red meat intake. Red meats are a natural source of creatine. Fish such as herring, tuna, and salmon all contain substantial amounts. If your diet is high in these types of foods, consider cutting back or eliminating intake. You can replace meat proteins with legumes or whey protein.
Step 4
Drink more water. According to the American College of Sports Medicine, since creatine is excreted in your urine, flushing out your system by drinking more water can help rid your body of excess creatine. Try to drink a minimum of eight, 8-oz. glasses of water per day to help eliminate creatine.

Increased urea and creatinine are mainly caused by renal failure or decreased kidney function. Kidneys work as filters in our body. Filtering the toxins out from our body and cleansnig the blood. If the kidneys are not working properly due to Diabetic nephropathy, Renal artery stenosis (genetic or due to chronic blood pressure) and other kidney diseases like renal cysts, malignancies, tumors, drugs and others.


2012/08/07

Can Polycystic kidney disease caused renal failure


Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes and extra fluid from the blood to form urine. They also regulate amounts of certain vital substances in the body. When cysts form in the kidneys, they are filled with fluid. PKD cysts can profoundly enlarge the kidneys while replacing much of the normal structure, resulting in reduced kidney function and leading to kidney failure.
When PKD causes kidneys to fail-which usually happens after many years-the patient requires dialysis or kidney transplantation. About one-half of people with the most common type of PKD progress to kidney failure, also called end-stage renal disease (ESRD). The duration from early stage Polycystic Kidney Disease to end-stage Renal Failure differs in different persons. A good nursing in daily life and timely treatment can all affect the duration. In addition, factors such as infections, not well controlled complications, improper diet, strenuous exercise, drinking or smoking can all aggravate the illness condition or fasten up the deterioration of Polycystic Kidney Disease into Renal Failure.
PKD can also cause cysts in the liver and problems in other organs, such as blood vessels in the brain and heart. The number of cysts as well as the complications they cause help doctors distinguish PKD from the usually harmless "simple" cysts that often form in the kidneys in later years of life.

How to Prevent Renal Failure for Polycystic Kidney Disease?

1. When the kidney is invaded by inflammation or stones the kidney tubules epithelial will appear phenotype transformation and then the permeability of cyst wall decreases so that the cyst liquid secreted by cyst wall can not be discharged out of human body. Then the cyst liquid will accumulate into the cyst which will lead to the increase in size of cysts along with the time passing by. So the key point to treat Polycystic Kidney Disease is to control and shrink the size of cysts and supply new nephrons to play renal function which should have been done by those necrotic nephrons.Keep good moods and avoid overwork. Follow the doctor’s advice. Have a light diet and eat more fruits. Control the intake of protein. It is better for your health to give up smoking and alcohol. When high blood pressure is serous and edema happens, restrict the salt intake. Properly exercise but avoid the extensive exercise.

2.keep a balanced diet
3.Active treatment

Micro-Chinese Medicine Osmotherapy and Immunotherapy is taken to treat Polycystic Kidney Disease, of which the former is used to repair the damaged kidneys by shrnking and controlling the cysts, and the later is applied to regenerate kidney functions by producing new nephrons.the active substance of Micro-Chinese Medicine can restrain the secretion of cyst wall epithelial cell; prevent the continuous expanding of bursa wall vessels and cyst. This therapy fundamentally controls the enlargement of cysts and repairs the damaged renal nephrons.




Blood Plasma Exchange Experimental Research Effects

Truth about blood plasma exchange
The basic principles of blood component replacement (apheresis) means by centrifugation or a membrane cell separator to eliminate cellular components (such as red blood cells, lymphocytes, white blood cells,platelets, plasma), the other components of transfusion to the patient. The eradication of one liter of plasma, blood decreased plasma protein lg/d1 However, because the balance and protein synthesis compartment, so it is necessary to exchange weekly 2.5 liters of plasma to plasma protein levels. About 509,6 of total IgG and 679/6 of a total of IgM. Nine of the period of three weeks 50mg/kg exchange, leaving only 5% of the original plasma. Eradication of plasma proteins and composition, depending on its charge, solubility, and other plasma protein pro-Heli, structure, synthesis and photo
The rate of incorporation. In the immune disorder, a combination of free inhibitor can slow down the immune globulin recovery. If you do not use of immunosuppressive agents, antibodies in the initial decline is visible after the
Now "antibodies anti-jump" or some of the antibody levels increased rapidly, to achieve blood components set tendency to change the value of the former base level, which is often associated with disease activity. Plasma usually by the United
Application albumin, salt and water replacement. Some of the complications of lupus (such as blood clots bloodBoard purpura) must use the new frozen plasma replacement. Plasmapheresis serious
Complications (such as low blood pressure, irregular heartbeat, infection), low incidence, reportedly less than 3%.
2 The application of  plasma exchange in SLE treatment can eradicate the cycle immune complexes(eg, free antibodies, complement components), changing and achieve great relievings in the patients. 

In a reported plasma exchange improve suppressor cells function in the other reports. Its selective eradication of the anti DNAIgG. Steven and other confirmed in the plasma set. After the change, monocytes kill the bacteria capacity to be improved; in the light disease, Tsokos found on mitosis original proliferative response of lymphocyte subsets percentage of no change. However, Wallace et al reported 17 cases of steroids or immunosuppressive. Inhibitor resistance in patients with lupus nephritis, B cells and T-cell count is normal,but to promote a mitogenic response and CD4 levels dropped after 15 plasmapheresis.

Blood Purification for Lupus Nephritis

Treatment lupus erythematosus is one involving the multi-system of the body organ, the complexity of the clinical manifestations, the prolonged course of repeated autoimmune diseases. Lupus erythematosus can be divided into two main categories of systemic lupus erythematosus and discoid lupus erythematosus. Subacute cutaneous lupus erythematosus, is a cross between skin lesions of discoid lupus erythematosus and systemic lupus erythematosus. The treatment of lupus erythematosus available plasma replacement method, the following is the introduction of plasma exchange method.

The treatment of lupus erythematosus through plasma exchange: plasma exchange, double filtration. Plasma adsorption: a rapid decline in the blood faster to improve the condition of antibodies and immune complexes, but still a short-term palliative expedient therapy required with the application of hormones and immunosuppressive agents. Concurrent infection, coagulopathy, water and electrolyte imbalance, and other side effects. And expensive.

Treatment of lupus erythematosus, plasma exchange method is suitable for severe lupus erythematosus associated with high levels of circulating immune complexes and acute diffuse proliferative lupus nephritis and glomerular sclerosis in patients with severe.

The treatment of lupus erythematosus, plasma exchange method is the blood of lupus patients, the introduction of a plasmapheresis device, the separated plasma was discarded, and supplement the inevitable fresh plasma or substitutes, such as 4% human serum albumin, and Ringer . Some patients before treatment to help clear soluble immune complexes and some antibodies, to accept this treatment the circulating immune complexes at high levels decreased significantly after treatment, and often get a good recent treatment. Plasmapheresis method in the treatment process prone to infection, coagulation disorders and complications such as water and electrolyte disturbance, this therapy can only be used as short-term adjuvant therapy in lupus treatment, not long-term use. Plasma exchange therapy can only clear the existing plasma immune complexes, but can not prevent these substances generated when treatment with hormones and immunosuppressive agents, in order to ensure safe and reliable treatment method: Each replacement from 1 to 1.5 liters, week 2 liters, minutes 2-4 times, repeat for a course of 2-3 weeks.

End-Stage Kidney Disease Caused by Lupus Nephritis Treatment Option

Systemic lupus erythematosus(SLE) is an autoimmune disorder. Cinically, approximately involvement of kidney injury occurs in approximately 30 cases. The condition in Lupus Nephritis greatly affect the prognosis in the patients. The patients with Lupus Nephritis and kidney failure have treatment options as follows:
Immunosupressive medications. 
Immunosupressive medications have the function to inhibit inflammations in the kidneys and thus reliving symptoms in the patients. However, Lupus Nephritis patients recurs easily because the treatments applied to them don;t help to improve kidney functions or correct the immune system at all. That's also the reason why the patients find difficulty in controlling their conditions. 
Dialysis
Dialysis is a way to reduce the wastes accumulated in the body so as to greatly reduce complications in brains, heart, gastrointestinal tract,  endocrine system, etc. As for the patients, dialysis is a temporary approach to get rid of the wastes in the body, however, it doesn't help repair kidneys thus it is suggested to adopt it as a temporary treatment instead of a life-long reliance. 
Kidney transplantation. 
Kidney transplantation substitute the failing kidney with a new one. However,applying immunosuppressive medications for life-long is indeed boring for the patients. in some, their creatinine level may increase within years, and in some they may return to dialysis again. 
Immunotherapy treatment is a comprehensive treatment which treats Lupus Nephritis from several aspects; first, the treatment can correct the immune system and recover immune disorder; second, the treatment can get rid of the antibodies, immune complexes and other wasteful products in bloodstream thus naturally reducing their further attack to kidneys; third, traditional Chinese herbal medicines are effective in repairing  injured kidney cells, improving kidney functions and thus hopefully getting away from dialysis in the patients. 

If a loved one has Lupus and kidney failure, effective treatments are the best ways to improve life quality in the patients. 

2012/08/06

Avoid kidney transplant with pkd patient

Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes and extra fluid from the blood to form urine. They also regulate amounts of certain vital substances in the body. When cysts form in the kidneys, they are filled with fluid. PKD cysts can profoundly enlarge the kidneys while replacing much of the normal structure, resulting in reduced kidney function and leading to kidney failure.

Kidney transplant is expected to replace one of the cysts-filled kidneys, leading a longer life. Compared with dialysis, transplant is considered as a better choice for dialysis hardly is cast off.

kidney transplant can not remove the cysts completely. What’s more, it will lead to damage to the kidneys. The final result will be dialysis and Kidney Transplant.
How to treat polycystic kidney disease other than kidney transplant and dialysis?

1. Traditional Chinese Medicine is an herbal remedy which is composed of natural herbs which can accelerate blood circulation, eliminate inflammation and shrink renal cysts naturally. Besides, it is designed to add the tonic herbs to repair the damaged renal tissues and refresh the poor kidney functions.

2. Immunotherapy is targeted at shrinking the cysts and alleviating hypoxia and ischemia in the kidneys. Actually it is not a single therapy; it is usually combined with medicated bath and food bath to take effects. They have the functions of dilating blood vessels, eliminating blood stasis, balancing disorders and removing metabolic wastes and toxins out of the body through blood circulation. This can help reduce the kidneys’ burden and increase the supply of blood, oxygen and other nutrition to the kidneys and provide necessary elements for the repairing of damaged renal intrinsic cells and tissues.you can see "New Perspective for Treating PKD : Immunotherapy"
learn about : Kidney Transplant Is not the Only Choice



Immunotherapy for End-stage Renal Failure caused by lupus

Systemic Lupus Erythematosus(SLE) is a kind of auto-immune disease, so the only thorough therapy for SLE is to regulate the abnormal immune system, not just to take some immunosuppressive medications to prevent the abnormal immune response, actually, when the abnormal immune response is prevented, the normal immune response also will be affected, leading to serious side effects.

End-stage renal disease is one of the most significant complications of systemic lupus erythematosus . Previous investigators have evaluated the morbidity and mortality of different renal replacement treatment modalities in these patients. Earlier reports have suggested that the systemic manifestations of SLE diminish, or "burn out," once ESRD occurs. These investigators also suggested that vascular access complications were a significant cause ofmorbidity and mortality in these patients treated with hemodialysis ( HD ). A retrospective review of the records of6 patients with ESRD from lupus nephritis (LN), who received both HD and peritoneal dialysis (PD), was performed to determine i/there was a difference in disease activity between treatment modalities, using patients as se/fcontrols. The number of SLE flares was determined by clinical and/ or serologic studies, and prednisone dosages compared for each treatment modality. F our of the 6 patients continued to have active SLE after renal replacement therapy was begun. There were no significant differences in the number ofSLE flares or prednisone dosages while receiving either treatment modality .While PD eliminates problems associated with vascular access, both HD and PD )/ere effective forms of renal replacement therapy. Most patients in this study continued to have active SLE after commencement of dialysis, with no differences in disease activity noted during HD or PD.

Without thorough therapy, SLE is easy to lead to complications, judging from your test reports,
sorry to say your kidneys have been injured, besides, the test report showed that you have DVT,
Anticardiolipin antibody syndrome, one kind of auto-immune disease.
Do you the meaning of Creatinine level?
Creatinine level can reflect the toxin level in body, there are totally about 200 kinds of toxins
in body every day, if the kidneys are failed to work, those toxin will be accumulated into the
blood, testing Creatinine level can reflect the toxin levels in body. If only judging from the
Creatinine level, sorry to say about 60% of your kidneys have been injured, in other words, only
about 40% of your kidneys still work normally.
I think you have taken immunosuppressive medications, the medical effects of such medicines and
the side effects caused by such medicines, you should have known. Only depending on such
medicines can't help you much.
Is it possible for you to come to China for treatments?
Our hospital is located in China, we only treat kidney disease, now we are the largest kidney disease specialized hospital in China.Our hospital is set up in 1986, we mainly use Chinese herbal Medicine Therapy, supplemented by Western Medicine Therapy. As for SLE or Lupus Nephritis, we mainly adopt Immune Therapy in our hospital. Pls note Immune Therapy not refers to those immunosuppressive medication treatments,it's a kind of systemic therapy. Such therapy contains 6 steps, that is Immune Examination,
Immune clearance, Immune blocking, Immune tolerance,Immune protection,Immune clearance .
Learn about  Immunotherapy for Treating Kidney Failure Caused by Lupus Nephritis

2012/08/05

Renal failure is to choose dialysis or kidney transplantation


Dialysis is through the filter to selectively exclude certain substances in the blood. In other words, by artificial means the toxic waste, water and salt accumulation in the body in patients with renal failure drain, so that the physical condition of the patient's recovery or reach a healthy state. There are two currently used forms of dialysis: hemodialysis and peritoneal dialysis. Hemodialysis using a special machine to replace kidney function. Peritoneal dialysis the peritoneum of the human body acts as a filter and remove toxins. Either dialysis modality, can only temporarily exercise the functions of the kidneys, the body of toxins excreted temporarily saved the lives of patients. Not have a fundamental role for the treatment of impaired kidney repair, we can not effectively block the process of renal fibrosis. Final condition will worsen, but a matter of time. So dialysis is a "means" temporarily "relieve patient suffering.
Kidney transplant is surgery, organ donor kidney transplantation to the process of receiving a transplant patient's body. The possible sources of the kidney: family, spouse, close friend or brain death and during his lifetime to sign an agreement to donate organs. Of course, the best match of the kidney is usually from the transplant recipient brothers and sisters, because their genes with the most likely. Kidney transplantation is the treatment of kidney failure, the best way, because the kidney transplanted into the patient's body is almost completely replaced by
Kidney function and renal failure and allow patients to resume a normal life, get rid of the pain of life by dialysis. Unfortunately, not every renal failure patients have the opportunity to receive a kidney transplant. Because it is difficult to find a suitable replacement kidney.
Kidney transplantation is the best treatment for the treatment of end-stage uremia, compared with hemodialysis, it has the following advantages:
A, serum creatinine recovery or near normal levels, which significantly improved a range of symptoms in chronic uremia, nausea, itching, pericarditis;
Second, to avoid loss of nutrients caused by hemodialysis; and correct anemia, improve sexual function, making the patient physically be restored;
Restoration of social activities and work, increased movement and travel, and improve quality of life;
Fourth, from the overall macro perspective, can be reduced in patients with medical spending, greatly prolong life.

Why renal function loss can cause renal failure in patients with nausea and vomiting?


1, renal failure will be caused by increased blood urea nitrogen, urease to decompose urea to ammonia, thereby stimulating the gastrointestinal mucosa cause nausea, vomiting.
2, renal failure, urinary concentration function decline, so many patients with nocturia, caused the blood concentration, thereby causing elevated blood urea nitrogen, so Obviously the symptoms of nausea in the morning.
The experts recommend patients up in the morning, you should pay attention to add moisture to do so can make the blood would not concentrate, while allowing the blood urea nitrogen values ​​remained relatively stable. Thus avoiding the early morning when nausea or vomiting, exacerbation of the phenomenon.

How to treat Polycystic Kidney Disease Patients with High Creatinine


With the body of patients with polycystic kidney cysts increases, increased cyst squeeze the kidneys, causing renal damage, renal injury led to the metabolites creatinine can not be ruled out, resulting in creatinine increase.
[Polycystic kidney disease treatment requires attention to the following three aspects:]
1.Early treatment and prevention of complications: the most common complications of polycystic kidney disease patients with urinary tract infection, cyst rupture, hypertension, is also an important factor of aggravated or induced renal damage must be timely control and treatment. But should be aware of to avoid renal toxic effects of drugs in the treatment process.
2.Polycystic kidney disease patients, family care and nursed back to health: polycystic kidney disease renal failure is a chronic progressive disease, often leaving the disease due to mood changes, fatigue or diet disloyal, falls trauma increased. Polycystic kidney failure patients should keep their minds at ease, rest, to establish the confidence to overcome the disease, actively cooperate with the treatment.
3.In the early detection of disease, surveys and statistics found that 60% -70% of patients with polycystic kidney side of the tendency of the rate of onset between men and women is roughly equal.
4.How to treat Polycystic Kidney Disease Patients with  High Creatinine?
The micronized penetration therapy through the skin, blood, and human lower back, the meridian system, a direct role in adult polycystic kidney disease, renal lesions, the release of the highly efficient Chinese medicines, increased local drug concentration , bioavailability, direct effect on the renal lesions, renal lesions targeted positioning, the complete removal of immune complexes and necrotic tissue, with a clear thoroughly the role of strong efficacy of fast and durable to prevent the adult polycystic kidney disease to chronic the development of renal failure. Moreover, the micro-based traditional Chinese medicine penetrate the treatment of adult polycystic kidney disease has no pain, short course, quick, and self-treatment at home, shorten the hospital stay, saving advantages of invalid loss.

What are the complications of Chronic renal failure ?


Chronic renal failure patients how to eat? Chronic renal failure patients how to eat? Chronic renal failure is a serious chronic kidney disease, not only do harm to the patient's physical and mental health, but also to the patient's daily life and work a great impact. Chronic renal failure patients live year-round drug separated from the mouth of the day, feel pain, so much trouble to his family. Not just rely on drugs for the treatment of chronic renal failure, should pay more attention to food and drink. Renal failure patients should be science diet, science diet plays a big role in the rehabilitation of chronic renal failure.
(A) the symptoms of nervous system
Nervous system symptoms are the main symptoms of chronic renal failure. Early in renal failure, patients often have dizziness, headache, fatigue, comprehension and memory loss and other symptoms. As the disease increased irritability, muscle trembling, convulsions; last may progress to a lack of facial expression, lethargy and coma. These symptoms occur with the following factors: ① certain toxic substances accumulation may cause degeneration of nerve cells; ② electrolyte and acid-base balance disorder; ③ renal hypertension due to cerebral vasospasm, hypoxia, and capillary permeability increased, which can cause brain cell degeneration and brain edema.
(B) symptoms of cardiovascular system
Chronic renal failure due to the role of renal hypertension, acidosis, hyperkalemia, sodium and water retention, anemia, and toxic substances, etc., can occur in heart failure, arrhythmias and myocardial damage. Stimulate the role of urea (and possibly acid), aseptic pericarditis can also occur in patients with heart chest pain; medical news and pericardial friction rub. Severe pericardial cavity, cellulose and bloody exudate appears.
(C) digestive symptoms
The earliest symptoms of the digestive system of patients with chronic renal failure is loss of appetite or indigestion; exacerbations, anorexia, nausea, vomiting or diarrhea. The occurrence of these symptoms may be associated with the bacteria in the gut urease decomposition of urea to ammonia, ammonia stimulation of the gastrointestinal mucosa caused by inflammation and multiple superficial ulcers. The patients are often complicated by gastrointestinal bleeding. In addition, nausea, vomiting, central nervous system dysfunction.

Children with nephrotic patients with creatinine high swelling how to do?


Edema is an important clinical manifestations of the nephrotic syndrome, adult serum white to white, <3 g to edema, but children do not necessarily edema in 1 g%. Edema of the distribution of adult mainly subcutaneous, only edema side hydrothorax and children to the eye, often hydrothorax and ascites, but the foot edema, which may be tissue tension the sake of children's feet. Facial swelling with anemia pale looking to make up a typical "renal face. Therefore, parents should pay attention to the emergence of edema, the next well-known kidney disease hospital for everyone to talk about children with nephrotic edema.
Children with nephrotic edema is due to severe proteinuria (urine foam), lower serum albumin, plasma osmolality decreased intravascular fluid into the tissue gap caused by the effective hypovolemia, a nearly spherical cells stimulated renin - angiotensin hormone - aldehyde and ketone-axis active so that the kidney further retention, retention of water, edema to occur and develop.
But one thing to note, edema of the severity of the nephrotic syndrome severity, duration, and the prognosis is not directly related to severe edema does not determine prognosis.
Edema of children how to govern? Recommended in patients with kidney disease new therapy for kidney disease, classical prescription, prominent Chinese characteristics, treatment, diagnosis and treatment is the essence of traditional Chinese medicine, the treatment of kidney disease new treatments for kidney specialists summarize 20 years of clinical experience of the kidney disease treatment, combined with the patient's condition, vary from person to person, from place to place, and the time devoted themselves to developing kidney Kang series of prescriptions has made ​​remarkable efficacy in the treatment of nephropathy. Recommended in a specialist hospital for professional treatment of uremia - the well-known kidney disease hospital, the use of a new therapy for treatment of nephrotic, achieved good results

2012/07/31

What are the symptoms of renal failure, dialysis patients?


Most people toxins from the body after dialysis decreased, will feel comfortable on the body, but there are also washed uncomfortable proportion of patients, known as the dialysis disequilibrium syndrome. So what is dialysis disequilibrium syndrome? : Refers to in hemodialysis (usually refers only to the artificial kidney dialysis), effective dialysis induced body fluid volume and chemical osmotic equilibrium calibrated speed caused affected the balance of intracellular and extracellular osmotic pressure and the resulting series of renal failure not directly related to syndrome.
1.Alleviate symptoms of recurrence of artificial kidney dialysis or shortly after the 48h after the original has been reduced symptoms again, can be expressed as headache, nausea, vomiting air of confusion, convulsions, coma and even death.
2.Symptoms to improve the excess poison has been ruled out, but clinical symptoms did not have a corresponding improvement.
3 pathological reflex was positive and increased intracranial pressure
Diagnosis:
Alleviate the symptoms of the clinical features of hemodialysis appears again, the above clinical symptoms.
Laboratory tests of serum potassium and urea nitrogen, creatinine, has been a marked decline in the cerebrospinal fluid content is relatively high in some cases the clinical manifestations of cerebral edema.
Treatment trials to improve the patient's plasma osmolality, have a certain effect on the treatment of the symptoms.
Treatment programs (dialysis disequilibrium syndrome dialysis disequilibrium syndrome how is it treated?):
Dialysis speed slow down the artificial kidney dialysis speed, especially when repeatedly dialysis should slow down, but the impact of dialysis efficacy is not easy to be adopted.
(2) to prevent the plasma osmolality to reduce advocated plus hypertonic fructose, glucose, or diameter by adding dialysis fluid to compensate for the reduction reaction of the dialysis and plasma osmolality, but this method is easy to lead to high blood sugar osmotic pressure hyperlipidemia, therefore difficult to grasp.
(3) symptomatic treatment.

Why uremia (end stage renal disease) must dialysis


Uremia two diagnostic criteria in clinical practice, a fourth of the chronic renal insufficiency, chronic renal insufficiency based on the level of serum creatinine in China is divided into four: a renal decompensation, serum creatinine 133-177 (Scr) umol / L; two renal decompensation, serum creatinine (Scr) 177 443umol / L; three renal failure of (uremia early), serum creatinine (Scr) and 443-707umol / L; four uremia, serum creatinine (Scr)> 707umoll / L, respectively. Another is chronic kidney disease (CKD) Stage V chronic kidney disease (CKD) is a foreign based on glomerular filtration rate (GFR) is divided into five: 1 and GFR> 90ml/min/1.73m2; period, GFR, 60-89ml/min/1.73m2; 3, GFR, 30-59ml/min/1.73m2; phase, GFR, 15-29ml/min/1.73m2; and GFR <15ml/min/1.73m2 ( or dialysis).
Uremia, in fact, refers to almost all of fibrosis in kidney tissue, resulting in loss of kidney function, not the human body through the kidneys produce urine, and waste generated by the in vivo metabolism and excessive moisture can not be eliminated from the body, such as glucose, proteins, organic acids , sodium, potassium, sodium bicarbonate, acid-base balance disorders resulting in disorders of the human environment, as well as the endocrine function of kidney abnormalities such as: the secretion of renin, erythropoietin, active vitamin D3, prostaglandin exception. Modern medicine believe that uremia is a complex syndrome of loss of renal function, the body's internal biochemical processes generated by the disorder. Not an independent disease, known as renal failure syndrome, or referred to renal failure.
Uremic kidney failure as the disease progress metabolic disorders caused by the poison of the results. Uremia is not terrible, terrible complications of uremia, in particular, to uremia advanced, involving the heart, lungs, liver, spleen and other organs and systems, and each type of complications are life-threatening, so it should be from the early high degree of attention.
From the Western point of view, clinical serum creatinine (Scr)> 707, will be carried out hemodialysis, but the serum creatinine level is not the only indicator of hemodialysis. In conjunction with the general vital signs of patients with uremia, symptoms, clinical manifestations, and supporting test results to assess the condition, does require dialysis must be timely or urgent dialysis.
Dialysis is the artificial kidney - dialysis membrane and dialysis machines to remove kidney failure when the patient's body more water, toxins, to correct electrolyte and acid-base disorders. Dialysis membrane to separate the blood and dialysate cleared from the serum by the principle of diffusion and convection of water and toxins from the dialysate to supplement the lack of substance, such as alkaline ions and calcium ions. In general, the purpose of dialysis is to quickly bring down the body of water and toxins, alleviate the symptoms of uremic patients, prevention of complications.
Uremic patients due to the role of renal hypertension, acidosis, hyperkalemia, sodium and water retention, anemia, and toxic substances such as heart failure, arrhythmias and myocardial damage. Stimulate the role of urea (and possibly acid) can also occur aseptic pericarditis in patients with heart chest pain, smell and pericardial friction rub on physical examination. Severe pericardial cavity, cellulose and bloody exudate appears.
Dialysis is the most direct way to a rapid elimination of toxins from the body, the body produces a lot of toxins to life-threatening, immediately clear toxins, meet the basic environmental balance in the body, so that life can be maintained, and also bring to the next treatment time.
Another point to emphasize is not the law of dialysis can solve all problems, the control diet, drinking, smoking, alcohol, and to develop good habits, improve immunity.
In general, the weekly dialysis patients, a daily water intake The lOOml and 24 hours of urine output and anuria in patients with daily water intake does not exceed lOOml; patients with dialysis two times a week, daily water intake plus for 300ml 24h urine output and water intake in patients with anuria not more than 300ml; dialysis three times a week, daily water intake for the 500ml plus the amount of urine, the daily water intake in patients with anuria not more than 500ml. Water intake must be limited, otherwise it will result in edema; complications such as hypertension and heart failure. In hemodialysis patients into the water every day how much is good, should be based on the patient's specific circumstances. In principle, Expenditure and Revenues to maintain a balance. The amount of urine, vomiting and diarrhea volume, dominant negative water (400-600ral/24h the) and dialysis dehydration.
Intake including daily water intake, the sum of the water content in food and in vivo metabolism of endogenous water. Determine the water in the body fluid balance is the most simple method is to measure weight, dialysis patients should be weighed in a day, requiring dialysis during the weight increases in the l less than 1.5kg a short period of time the weight changes are result of changes in liquid water in the body. Dialysis patients can not rely on increasing the ultrafiltration to improve the day-to-day into the water, because of the large number of rapid ultrafiltration hemodialysis water will cause the drop in blood pressure, cramps, headaches and other symptoms, and chronic water overload to increase cardiovascular load. The consequences are bad.
As for the management of salt, usually avoid high salt foods such as salted fish, salted egg, bacon, pickles, sauce and a variety of pickled products, oliguria, edema, blood pressure, should be controlled salt intake intake, on behalf of the salt is not abuse. Patients with dialysis three times a week, the daily salt intake of about 4g weekly dialysis patients daily salt intake of 3g.
Therefore, the high toxins in the body of uremic patients to stimulate cholestasis is extremely dangerous to life, we must implement the dialysis quickly to eliminate toxins from the body, meet the basic environmental balance in the body, so that life can be maintained.

Dialysis whether lowering serum creatinine


Dialysis whether lowering serum creatinine
First, what is serum creatinine? Serum creatinine (Scr) and endogenous creatinine (from decomposition of the body creatine from the formation constant, from the influence of food ingredients) and exogenous creatinine (derived from the intake of fish, meat food). Serum creatinine also known as serum creatinine, generally considered to be endogenous creatinine, endogenous creatinine is a product of the metabolism of human muscle. In muscle, creatine is mainly by the irreversible non-enzymatic dehydration reaction slowly constitute creatinine, and then released into the bloodstream, with the urinary excretion. Thus closely related to serum creatinine and total body muscle and less susceptible to dietary influence. Creatinine small molecules can be filtered through the kidney ball very little absorption in the renal tubules, creatinine the body produces daily, almost all with the urine, are generally not subject to the urine output impact. Clinical detection of serum creatinine is one of the main way of common understanding of renal function.
Creatinine level more than half of the intrinsic cells for kidney patients, under normal circumstances means that the kidney is healthy at least damage. Because creatinine level? how to reduceCreatinine level ? Creatinine level how the treatment? The causes of elevated serum creatinine? Creatinine level is due to intrinsic renal cell injury, leading to kidney original functional disorder, with the damage kidney more and more intrinsic cells, gradually increased the scope of kidney function is lost, the toxins from the body can not be excreted, resulting in increased laboratory tests of serum creatinine. When serum creatinine height exceeds 707umol / l, which means the patient's condition has been developed to uremia stage.
Creatinine level how the treatment? In general, the creatinine level generally use western medicine for detoxification, but, after a long period of clinical observation, we found that western medicine detoxification treating the symptoms not the illness, only temporarily serum creatinine down, those are surface phenomena, generally maintained 2-3 times per week dialysis assisted detoxification, or after a certain period of time, serum creatinine will rapidly increased.
Serum creatinine increased renal fibrosis, with normal nephron filtration function is replaced by fibrous tissue, loss of detoxification function. Stones is due to colloids and crystal metabolic imbalance due to the body, and infection, nutritional and metabolic disorders, urinary tract foreign body, urine smoldering and geographical and climatic factors. But strong growth to a certain period will lead to renal parenchymal damage, and now the key to treatment is inherent in the gravel at the same time repair the kidney cells, the renal parenchyma, a comprehensive repair, eliminate the cause from the fundamental, it is recommended that you use Chinese medicine to regulate system treatment programs. Because Chinese medicine does not contain any hormones, and the prognosis is not easy repeated.
· Kidney disease hospital the TCM holographic machine due to intervention therapy with the comprehensive treatment of live kidney series of prescriptions, which can effectively repair the damaged functional nephron. TCM holographic machine intervention therapy, drugs active ingredients penetrate through the acupuncture points spread to the kidney, active through the kidney, blood circulation, lowering cloud detoxification by means activate kidney function to clear the kidneys, for the purpose. TCM holographic machine intervention therapy can promote and improve the already shrinking the necrosis of the kidney microcirculation, accelerate the metabolism of the diseased kidney, so that the active ingredients in drugs to fully play its role, to repair damaged glomerular enhanced glomerular reabsorption, restore kidney normal the physiological function of serum creatinine, blood urea nitrogen decreased to normal.

Patients with renal insufficiency inherited?


Ward which often have patients ask me, patients with kidney disease is not genetic, based on clinical experience and related information, most of the kidney disease is not hereditary. So far found in polycystic kidney disease is genetic history there is a latency in the body, if they are felt factors, will be the incidence of
Caused by renal insufficiency can be many causes, most of the causes of renal dysfunction is not hereditary, but it is worth noting is the cause of renal insufficiency, there is a hereditary nephropathy, for example, polycystic kidney disease is one of them, clinical, polycystic kidney disease is divided into autosomal dominant polycystic kidney and autosomal recessive polycystic kidney, the former is more common, the latter rare, a genetic disease due to familial aggregation, therefore, polycystic kidney disease caused by renal insufficiency with a certain genetic color, we recommend, the best of this class of patients considering having children at the same time considered from the perspective of prenatal and postnatal care, and to take effective treatment measures, positive patients with renal insufficiency. From clinical experience, the doctrine of the original master of the Spleen "and" β-like immune conditioning "therapy of chronic renal insufficiency have a good therapeutic effect.
In addition, for patients with essential hypertension, but also should be noted that, due to high blood pressure is easy cause of renal insufficiency, renal insufficiency, one of the reasons this part of the patients also need to be vigilant heart, experts said, may genetic hypertension, renal insufficiency, the situation

Why Uremic patients not have sex?


Uremia is it? Urine inside is literally no toxins, the most simple clinical patients can be seen, the patient's urine, the smell is very light, the color is very pale, serious enough to see urination no color, no odor, which is the kidneys can not be excluded toxins, water, not metabolism of the body out of toxins from the body due to accumulation of toxins, the body's internal biochemical process disorder resulting from a complex syndrome.
Renal, endocrine function, juxtaglomerular cells may secrete renin, renin, intrahepatic synthesis of angiotensinogen into angiotensin I, the latter in the lungs angiotensin converting enzyme generated angiotensin II vasoconstriction with a strong blood pressure and stimulate aldosterone secretion. Device can generate juxtaglomerular erythropoietin factor, the factor of the role of EPO in the heyday of the liver, red blood cells, making the conversion, but also regulate water and electrolyte acid-base balance, is the human body in a relatively stable internal environment, and ensure normal the victory of activities.
In patients with uremia toxins from the body is too high, and will be accompanied by varying degrees of water and electrolyte acid-base balance disorder, cause 1) the hypothalamic - pituitary - gonadal dysfunction: in uremic patients because urinary toxins affect the endocrine system, caused by the abnormal;
(2) organic: about 90% of patients with autonomic nervous system or penile vascular occlusion, about 56% of patients had severe sexual dysfunction, and another 20-30% of patients have mild or moderate sexual dysfunction; these organic damage may be caused because of uremia or the reasons for the original cause of chronic renal failure;
(3) uremia itself;
(4) uremic complications: such as the excitement of parathyroid function, anemia, cardiovascular disease, stroke, infection, malnutrition and other problems;
(5), fatigue, psychosocial factors, depression and other problems

2012/07/28

Treatment for Renal Failure Induced by Glomerularnephritis

Glomerulonephritis and renal failure are renal disease, among them there is a connection! Generally speaking, glomerulonephritis, renal failure due to Suffering from nephritis, if long-term therapy ultimately will develop into renal failure. Is not the same way for both treatment and care. So, how to distinguish between glomerulonephritis and renal failure is very important.
How to distinguish between glomerulonephritis and renal failure? Glomerulonephritis:
The clinical manifestations of this disease occurs mainly in children and adolescents, more men than women. Common manifestations are as follows:
Edema To start the eyelids start, and gradually spread to the body and even the chest, ascites;
② blood pressure is elevated;
The ③ hematuria mostly wash the meat in water samples associated with proteinuria, urinary tube;
④ most of them have varying degrees of renal impairment, the most obvious change in glomerular filtration rate.
The first two weeks of bed rest, wait for his condition improved significantly and gradually get up activities, generally a break of not less than two months; diet is generally given to the animal protein, adequate calorie and vitamin-rich foods; give a low-salt or no salt diet according to the degree of edema severe edema should limit the intake of water, vomiting, not eating should be intravenous the lonely rehydration and antiemetic; edema or oliguria should use diuretics, high blood pressure, use of antihypertensive drugs; use of penicillin to prevent infection.
How to distinguish between glomerulonephritis and renal failure? Renal failure:
① start of this period, patients often suffer from some known of the etiology of ATN, such as hypotension, ischemia, sepsis and renal toxins, but not yet renal parenchymal damage in acute renal failure at this stage can prevent. as renal tubular epithelial obvious damage, GFR a sudden drop in the performance of acute renal failure syndrome in the clinical became apparent, then enter the maintenance phase.
② maintenance phase, also known as oliguria. Typical for 7-14 days, but can also be as short as a few days, as long as 4-6 weeks. Glomerular rate remained at a low level. Many patients, there may be oliguria (<40Oml / d). but some patients can no oliguria, urine output more than 400ml / d, referred to as non-oliguric acute renal failure, the disease mostly light, with good prognosis, however, regardless of urine output to reduce, with the renal dysfunction in clinical practice can be a series of uremia performance.
③ infection is another common and serious complications of acute renal failure in acute renal failure at the same time or in the development of the disease process can also merge multiple organ failure in patients with mortality as high as 70%.

When Will Dialysis be Prescribed to in Diabetic Nephropathy

Diabetic nephropathy requiring dialysis? Development of diabetic nephropathy to the late usually complications of renal failure, this time is generally required dialysis, diabetic renal failure, dialysis and other chronic kidney disease caused by uremia, compared with a certain degree of particularity.

Diabetic nephropathy is a common complication of diabetes, is one of the manifestations of diabetic systemic microvascular disease, as the disease progresses in later stages of diabetic nephropathy in patients with elevated serum creatinine in patients with diabetic nephropathy increased serum creatinine, and you will be prompted the kidney has a serious injury.

Treatment of diabetic nephropathy need to:

As soon as possible to carry out dialysis. General idea of ​​dialysis carried out earlier, the serum creatinine the in 420umol / L, endogenous creatinine clearance rate of 10 ~ 15ml/min or uremic symptoms may be considered to carry out dialysis patients with diabetes is often associated with vascular disease, fistula mature relatively long time, so ostomy surgery should be made sooner.

Dialysis process should be monitored for blood glucose levels, blood sugar after dialysis should not be higher than 8.8mmol / L.

, Dialysis should ensure that the full water and solute removal, dialysis three times a week is more appropriate, less short-term dialysis. Another course of treatment can not simply rely on dialysis, which can only play the role temporarily replace kidney function.

Fourth, the dose of heparin, at least with non-diabetic dialysis, or slightly higher.

The same in patients with diabetic nephropathy need to clear diabetic nephropathy is not a simple dialysis, dialysis only provide a good environment for the repair of post-renal and dialysis should also select the appropriate ways and means of their own treatment of the disease. Dialysis at the same time, with the characteristics of traditional Chinese medicine therapy ---- of micro-penetration therapy of Chinese medicine, traditional Chinese medicine active substances play to improve the patient environment within the disordered state, to improve the status of renal ischemia and hypoxia, anti-inflammatory, antithrombotic, providing repair required the multiple effects of various nutritional elements, and ultimately intrinsic cells repair the kidney and restore renal function to avoid the purpose of the final treatment of recurrent disease.

Potential Life Barriers faced to patients after Kidney Transplant (Transplantation)

What is a kidney transplant?Kidney transplantation, commonly known as "transplant" a lot of people, literally, that the kidney transplant necrosis of the kidney excised, re-transplant a healthy kidney is a new kidney and old kidney exchange surgery. In fact, this is a wrong understanding of kidney transplantation.So, what is kidney transplantation? Kidney transplant a healthy kidney implanted in the iliac fossa of the patient's right lower quadrant, with the new kidney to replace the original kidneys work, the original patient necrosis of the kidneys continue to exist in the patient's body. The new kidney transplant select the internal iliac artery anastomosis, vascular anastomosis, until the new kidney blood supply in good condition, then sutured patients with abdominal wall to complete the surgery.What factors will affect kidney transplantation?Although kidney transplant is an effective treatment of renal failure, uremia patients, kidney transplantation is not everyone can do. Kidney transplant in the actual implementation constraints influence by many other conditions.First, the economic conditions. Under normal circumstances, to do a kidney transplant, surgery, care, inspection fees, bed charges fees, takes about 7 - 100 000. Thereafter, the kidney transplant every year need to use at least 2 - 30 000 more than the anti-rejection drugs to maintain.Second, the kidney source. Each year tens of millions of renal failure patient's condition to enter late and need a kidney transplant, but can provide the number of kidneys are extremely limited. Numerous uremic patients only death in the days of waiting for a kidney.With type. Kidney transplants between parents and children the most affordable. But the vast majority of kidney transplant patients need to use someone else's kidney to sustain life. However, the own circumstances and kidney matching success rate is very low, it has also become a kidney transplant to be one of the major influencing factors.Fourth, the survival rate after surgery. Kidney transplant is an effective treatment in patients with advanced uremia means, but survival after kidney transplant is directly related to the transplant patient's living conditions. Under normal circumstances, the year after kidney transplant survival rate is nearly 90 percent a year for 70% -90% in the next few years, each year about 5% -8% of patients with renal transplantation or renal graft death.Level of medical treatment of kidney transplant surgery. Even if the above conditions are met, but the kidney transplant is not anywhere arbitrary. At present, many regions in China and hospitals, due to the limited level of medical conditions and medical personnel are not able to carry out the conditions of the kidney transplant.Analysis of the pros and cons of renal transplantationBy a kidney transplant, uremic patients can significantly improve survival of the state to extend late life. This is the biggest advantage of renal transplantation for end stage renal disease patients. However, after a kidney transplant, the patient did not sit back and relax. After renal transplantation, uremic patients need to withstand a wide range of negative effects:Rejection after renal transplantation is difficult to avoid, patients need to take lifelong anti-rejection drugs. Long-term use of these drugs, will largely reduce the patient's immune function, causing liver and kidney toxicity, high blood sugar, osteoporosis and other complications.Complications after renal transplantation is inevitable. After renal transplantation, uremic patients are often prone to infections, heart failure, abnormal liver function, endocrine and metabolic disorders, cancer and other complications. More serious is that part of the kidney transplant patients may also have kidney disease relapse, resulting in kidney transplant lost its meaning.Long-term survival after renal transplantation. Kidney transplant, short-term effect has been very satisfactory, more than 90 percent of the one-year survival rate of uremic patients. But the results are not satisfactory in the long run, after renal transplantation, 5-year survival rate is greatly reduced.

Can Stage 3 Chronic Renal Failure Be Reversed

Can Stage 3 Chronic renal failure can be reversed?


  Stage 3 
Chronic renal failure can be reversed under certain conditions, the reversible factors include: 
① The effective hypovolemia: sodium and water loss, bleeding, etc., enable the glomerular filtration rate, aggravated renal failure; 
② infection : The common causes of respiratory tract, urinary tract and skin infections, including some of the occult infection;
 ③ urinary tract obstruction: The most common cause of urinary tract stones, including complete or incomplete obstruction; 
④ nephrotoxic drugs: The most common The reason for the use of aminoglycoside antibiotics and contrast agents; 
⑤ serious cardiovascular disease: severe hypertension, congestive heart failure, serious arrhythmias, and cardiac tamponade;
 ⑥ The acute stress: such as planing serious injury after major surgery
⑦ hypercalcemia, hyperphosphatemia or metastatic calcification; 
⑧ high-protein diet.

    
Chronic renal failure in the early treatment delay progression of the disease and better patient prognosis is of great significance. In advanced chronic renal failure patients, diet and medication can make it to the relief of symptoms, so that dialysis was delayed. In the application of non-dialysis treatment, the need to nutritional therapy based on, and with the application of drugs to slow the progress of chronic renal failure, azotemia patients should not be treated with intestinal catharsis or oral adsorption therapy. In short, we should strengthen the comprehensive treatment of all aspects of reducing the symptoms of chronic renal failure, and improve patients' quality of life and delay disease progression.  
How to slow down progression of stage 3 chronic kidney failure?
Slow down the progression of stage 3 chronic renal failure should be a comprehensive treatment, including the following measures: ① treatment for the cause: there are many causes of chronic renal failure caused by chronic nephritis, lupus nephritis, purpura nephritis, lgA nephropathy, diabetic nephropathy, need adhere to the long-term treatment. ② to eliminate the deterioration of renal function factors: to remove the factors that aggravate the deterioration of renal function, such as infection, hypertension, urinary tract obstruction and electrolyte imbalance, especially to control high blood pressure is of great significance in delaying the development of chronic renal failure. Angiotensin-converting enzyme inhibitors application of chronic kidney disease such as diabetic nephropathy and other glomerular filtration to reduce the role, can reduce proteinuria and to enable the serum creatinine level increased to slow down. ③ diet therapy: low protein, low phosphorus diet, alone or plus essential amino acids and α-keto acid, is more favorable to apply the α-keto acid. The method may reduce glomerular filtration and tubular high metabolic role. ④ correct hyperlipidemia: It has been confirmed hyperlipidemia can increase the inflammation of the kidneys and promote the hardening of the kidney, the unsaturated fatty acids and lipid-lowering drugs may slow down glomerulosclerosis. The ⑤ reduce the accumulation of uremic toxins: such as low-protein diet, oral adsorption therapy and gastrointestinal dialysis. Application of of ⑥ anticoagulant drugs: anti-platelet drugs and blood circulation, the drug may reduce the renal microcirculation thrombosis, slow down the role of glomerulosclerosis or renal interstitial fibrosis.

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