2011/12/31

renal failure symptoms

Kidneys are bean-shaped organs located on both sides of the spine of the human body, below the rib cage. Kidneys help excrete the waste products along with excess water. As blood passes through kidneys, waste products and toxins are removed from the blood and electrolytes are preserved in the body. Kidney failure is said to occur when kidneys are not able to rid the body of the harmful toxins and excess fluid. In scientific language, it can be said that a decrease in the glomerular filtration rate indicates renal failure. The toxic blood and excess water which gets accumulated in the body can lead to several health complications which can be at times fatal. Therefore it is necessary to know the symptoms of renal failure.
Renal Failure Symptoms
Acute Renal Failure Symptoms
A sudden or acute renal failure (ARF) occurs when blood supply to the kidneys is interrupted or reduced all of a sudden. A sudden injury or accident is generally responsible for ARF. Here are theacute renal failure symptoms.
Dryness of mouth
Greatly reduced urine output
Abdominal pain
Drowsiness
Loss of appetite, lethargy
Stomach upset, nausea, vomiting
Anxiety, headache, restlessness
Water retention or body swelling (specially legs and feet)
Back pain

Milk and Kidney Failure

Why Are Patients with Kidney Failure Recommended to Drink Milk?
Milk belongs to one kind of protein. In principle, patients with Kidney Failure are not recommended to take food rich in protein in case of the increase of BUN and the occurrence of acidosis. Hence, patients should limit the intake of protein due to the inability of the kidneys to remove excess BUN and regulate acid-base balance in body.
Well then, why are patients with Kidney Failure are allowed to drink milk? It is because milk belongs to high-quality protein. Though patients are limited to take food rich in protein, they are allowed to take food rich in high-quality protein properly so as to meet the need of their body.
2. Milk-High-Quality Protein:
1) The content of high-quality of protein in milk accounts for 80 % of the total protein with full range of amino acids. And the high-quality protein is easier to be absorbed and taken by human body comparing with vegetable protein.
2) The calcium and potassium in milk are in proper proportion, which can help regulate patients who experience disproportion between calcium and potassium.
3) Due to the fact that patients with Kidney Failure take less protein, they are not overly restricted to take heat. The content of fat in milk is about 2%-3.2% and the fat is very easily to be absorbed.
4) The content of lactose is not high, about 10g. In this condition, even patients with Diabetes Nephropathy can drink a bag of milk without white sugar in it.
It is worth noting that patients in End-Stage Kidney Failure should have limited the intake of water. The content of water in milk is high, so patients should calculate the content of water in milk.

2011/12/29

Common Sense on Acute Renal Failure

The course of Acute Renal Failure can be divided into three periods:
ⅠClinical manifestations of oliguria period:
High blood pressure, pulmonary edema, heart failure and cardiac arrest occur due to the retention of water and low sodium in the body, and hyperkalemia, which are caused by the obviously decreasing renal filtration rate.
ⅡClinical manifestations of polyuria period:
●At the beginning of polyuria period, the symptom will not be improved, however, even worse, and the patients will feel better when urea nitrogen and creatinine start to decrease.
●As a result of polyuria, the edema will disappear, and urea nitrogen and creatinine will gradually return to normal after one week. On the other hand, dehydration will happen, which is accompanied by low serum sodium and hyperkalemia following electrolyte excreted together with urine.
Ⅲ Clinical manifestations of recovery period:
This period will last for 6 months, during which the function of patient will become normal day by day. The abnormal condition of renal function indicates the permanent damage on kidney.
Nursing diagnosis
ⅠExcessive body fluid is related to the damaged renal filtration.
ⅡThe risk of infection is related to the limited intake of protein, dialysis and the declined immunity
ⅢPotential complications: high blood pressure, cardiac arrest, arrhythmia, pericarditis, etc.
Nursing care
ⅠObservation: Observe signs of life and record 24 h output and intake.
Ⅱ Strictly control the intake of fluid:
the intake of fluid= 500ml + the output of the day before
Ⅲ Diet nursing
1. The patients who can eat should be provided with light liquid or semifluid meal, and limited water, sodium salt, sylvite and protein.
2. The patients who cannot eat should be provided with high quality of protein by intravenous injection.

Neglected Symptoms in Early Stage of Renal Failure

The symptoms neglected at early stage of Renal Failure include:
1. Hypoglycemia (low blood sugar)
When there is Renal Failure, the insulin in the body can not be effectively inactivated, which causes the Diabetes Mellitus patients with high blood sugar to show the symptom of hypoglycemia.
2. Anemia:
Renal failure causes the erythropoietin to decrease which is produced by normal healthy kidney, which leads to hypodynamia, anemia and so on.
3. Fracture:
Renal failure causes vitamin d3 which regulates the metabolic activity of calcium and phosphorus to decline, so the patient may easily fracture.
4. Epistaxis (nosebleed):
Renal failure causes the function of coagulation to decline, which is the reason of bleeding from nose regularly.
5. Heart Failure:
The toxin and acidosis in the Renal Failure patient’s body restrain the systolic function and diastolic function of myocardial cells, which results in Heart Failure.
6. Feminization in men:
Estrogen in Renal Failure patient can not be effectively inactivated, which causes male patient to have breast augmentation and less body hair which are the female’s features.

2011/12/23

How Does Dialysis Help Patients with Kidney Failure

What is Dialysis?
Dialysis is also called artificial kidneys, which, to some extent, can really replace kidneys to do a lot of work when people's kidneys cannot do their job well.
Normal kidneys have their functions to excrete helpful substances (prostaglandin and erythrogenin) so as to regulate blood pressure and provide enough blood to human body.
Kidneys can also remove waste and toxin from human body, so that people's inner environment can be kept clean.
Kidneys help maintain the proper levels of fluid in body so as to prevent dehydration or fluid retention.
Dialysis, as an artificial kidney, can partially replace kidneys to play its function to discharge toxin and remove extra water in body. It seems that dialysis treatment is the only effective method to keep the inner environment of body clean.
When do Patients with Kidney Failure Receive Dialysis?
In the early stage of Kidney Failure, patients are more likely to get a better recovery with the help of conservative treatment, such as some herbal medicines. In this condition, it is not necessary for patients to take dialysis.
If patients who are at the early stage of Kidney Failure didn't pay attention to their disease or get effective treatment, they are prone to the End-stage Kidney Failure. If so, patients have to receive dialysis to help them remove toxin from their body.
Note that one main index that can be used to judge whether patients should receive dialysis is the serum creatinine level. Generally, patients with the creatinine level of 450mg/ dL are recommended to receive dialysis. Whether patients will receive dialysis mainly depend upon their own disease condition and their local reference values of creatinine level.

2011/12/18

Renal failrue

What is acute renal failure?
Acute renal failure (also called acute kidney injury) means that your kidneys have suddenly stopped working. Your kidneys remove waste products and help balance water and salt and other minerals (electrolytes) in your blood. When your kidneys stop working, waste products, fluids, and electrolytes build up in your body. This can cause problems that can be deadly.
What causes acute renal failure?
Acute renal failure has three main causes:
A sudden, serious drop in blood flow to the kidneys. Heavy blood loss, an injury, or a bad infection called sepsis can reduce blood flow to the kidneys. Not enough fluid in the body (dehydration) also can harm the kidneys.
Damage from some medicines, poisons, or infections. Most people don't have any kidney problems from taking medicines. But people who have serious, long-term health problems are more likely than other people to have a kidney problem from medicines. Examples of medicines that can sometimes harm the kidneys include:
Antibiotics, such as gentamicin and streptomycin.
Pain medicines, such as aspirin and ibuprofen.
Some blood pressure medicines, such as ACE inhibitors.
The dyes used in some X-ray tests.
A sudden blockage that stops urine from flowing out of the kidneys. Kidney stones, a tumor, an injury, or an enlarged prostate gland can cause a blockage.
You have a greater chance of getting acute renal failure if:
You are an older adult.
You have a long-term health problem such as kidney or liver disease, diabetes, high blood pressure, heart failure, or obesity.
You are already very ill and are in the hospital or intensive care (ICU). Heart or belly surgery or a bone marrow transplant can make you more likely to have kidney failure.

2011/12/17

Delay the Development of Renal Failure

There are some measures for delaying the development of Renal Failure.
Ⅰ Constantly see a doctor:It plays an important role in delaying the development of Renal Failure. The patients can receive rational treatment and good guidance, which can reduce or prevent some inducements of Renal Failure, including damage from medication, insufficiency of blood volume from dehydration, hyperlipemia, hypercalcemia, hypokalemia, urinary tract obstruction, infection and massive haemorrhage, etc.
Ⅱ Rational diet: The research depending on a large amount of experiments and clinical observation indicates that low-protein diet and (or) low-phosphorus diet can delay the development of Renal Failure in most cases, and even stop the development of Renal Failure. Low-protein diet added necessary amino acid can reduce the high filtration state of Chronic Renal Failure.
Ⅲ Control blood pressure: To control Renal Hypertension and primary hypertension can delay the development of glomerulosclerosis. The former depends on controlling the high perfusion to glomeruli, while the latter depends on taking medications.
Micro-Chinese Medicine Osmotherapy: It is an external therapy which does not have any side-effects as some oral medication. Micro-Chinese Medicine Osmotherapy can play a vital role in dilating blood vessels so as to remit the high blood pressure condition. Besides, eliminating the wastes and toxins which are overloaded to kidneys is another function of Micro-Chinese Medicine Osmotherapy. This therapy can provide your kidney good internal environment for further treatment such as stem cells transplant .

High Levels of Glucose Leads to Kidney Failure

How Does High Levels of Glucose Occur?
Generally, glucose will be delivered into body cells for energy after people eat food. That is to say, there is no or a small certain glucose in blood. However, glucose level will rise due to the insulin resistance caused by immune system or no insulin or less insulin produced by the islet cells.
Poorly Controlled Glucose Level:
If patients' glucose level is controlled well, their kidneys may not be damaged. It is high levels of glucose that damage their kidneys.
In order to discharge extra glucose in their blood, their body tries to do this job. And then a certain amount of glucose will be discharged along with the urine.
But too much glucose builds up in their kidneys, the blood vessels in their kidneys will be damaged gradually.
A Small Amount of Protein in the Urine:
In the early stage of kidney damage, there is no overt symptoms. But there is a small amount of protein in their urine, which may indicate the kidneys have been damaged.
A Large Amount of Protein in the Urine:
When a large amount of protein in the urine occur, the kidneys are damaged severely. In this stage, patients are experiencing Kidney Failure.
How to Decrease the High Glucose Level?
Stem cells treatment can help patients decrease high glucose level by differentiating islet cells.
How to Repair Damaged Kidneys and Improve Kidney Function?
Stem cells can differentiate kidney cells to replace necrotic ones, which increases normal kidney units and then kidney function will be improved accordingly.

Prevent Childhood Nephrotic Syndrome from Progressing to Kidney Failure

1. What will Cause or Stimulate the Occurrence of Kidney Failure?
1) Frequent Relapse
Childhood Nephrotic Syndrome is easy to relapse since it is not treated from the root causes. Besides, it is more likely to relapse when patients experience infection or cold. Frequent relapse of it will
Infection or cold may cause the relapse of it
Some patients may be recommended to take some renal toxic drugs, which will damage the kidneys and burden the kidneys. Taking renal toxic drugs in a long time, the kidneys are more likely to be severely damaged.
2. Micro-Chinese Medicine Osmotherapy:
This therapy is externally used by skin, meridians and collaterals and then kidney lesion with the help of osmosis device and penetrant. Children only need to lie on two small bags of powder medicine to receive treatment. It takes about 45 minutes.
This kind of medicine is mainly composed of herbs that has no side effect on children. So far, no one receiving this treatment is sensitive to herbal medicines.
3. How Does Micro-Chinese Medicine Osmotherapy Work on Childhood Nephrotic Syndrome?
After the medicines are permeated into kidney lesion, the kidney lesion will be repaired gradually. Once the kidney lesion is repaired, the edema or urine protein will be eliminated.

2011/12/14

renal failure cases

She was diagnosed bronchial asthma, pulmonary emphysema, moderate anemia, renal failure in a hospital. For poor treatment effects, she was transferred to other hospital for further treatment. The results of related examination are serum creatinine: 380mmol/L; urine protein: 2++. She was diagnosed with chronic bronchitis, chronic kideny failure, renal hypertension, and renal anemia. The doctor made a treatment plan of relieving cough and asthma, giving drugs to protect kidney, the symptoms were improved. The doctors in that hospital suggested that she receives dialysis when the creatinine level reaches about 700mmol/L.
 Mary was discharged from hospital, but before long, she was attacked by the disease again. Nausea, vomiting and dizzy presented.   Creatinine level increased to 480 mmol/L; urine protein: 3+. The disease was serious at that time.
Mary was always looking for better treatment after she found micro-Chinese medicine, which treats renal failure effectively.  When Mary was hospitalized, the test results are 480 mmol/L and protein 3+. The disease is controlled well after about one month’s treatment. The creatinine level in blood has decreased to 300mmol/L. The result of protein in urine is negative.

2011/12/13

Are There Advanced Medicines for Chronic Kidney Failure

There are mainly two kinds of orally used medicines: Chinese Medicine and Western medicine. For patients with Chronic Kidney Failure, they always take hormone (prednisone), immunosuppressive agent or cytotoxic agents (cyclophosphamide) to eliminate the symptoms, such as proteinuria and edema. However, patients choose Chinese Medicine gradually, such as cordyceps to repair their damaged kidneys due to the side effects resulted from taking hormone in a long time.
Externally Used Medicines:
Considering orally used Chinese medicines taste a little bitter, the other type Chinese medicine-externally used medicines are developed, which is called Micro-Chinese Medicine Osmotherapy.
After the effective medicines are permeated into kidney lesion, patients' kidneys will be repaired gradually through dilating blood vessels, anti-inflammation and degrading extracellular matrix. And then ischmia and anoxia condition will be improved and normal kidney cells will not be further damaged. If so, the damaged kidney cells will be repaired gradually.
Once the damaged kidney cells are repaired, the kidney function will be improved accordingly.
However, Micro-Chinese Medicine Osmotherapy only can repair the damaged kidney cells rather than the necrotic ones. In this condition, Stem Cell Transplant is adopted to differentiate new and healthy cells to replace the dead kidney cells. By this way, the kidney function is more likely to be greatly improved.

Some Symptoms Help You Know Kidney Disease Early

● Sleepiness and Fatigue
It may be the earliest symptom of kidney disease, which is also the easiest one to be ignored. However, many things can cause to be sleepy and fatigue. Many people will consider work strain and fatigue as the cause. If we get more rest, the symptom will get improved, and that is why this symptom of kidney disease is so easy to be ignored.
● Yellowish Face
This symptom is caused by anemia, the onset and progression of which are slow, so it is difficult to find out the difference in a short time.
● Edema
It is relatively easy to find out this symptom. When damaged kidney can not eliminate excessive water, water retention causes this symptom. At the early stage of kidney disease, edema just appears in eyelids and ankle, which will disappear after having a rest.
● the Change of Urine Output
Sometimes, because of decreased renal filtration function, the urine output will reduce according to the development of kidney disease. Even if the urine output is normal, wastes and toxins which should be excreted by kidney will be less in the urine. However, urine output can not exactly indicate the damage of kidney.
● High Blood Pressure
When our kidneys are damaged, our kidneys will secrete some substance which can cause elevated blood pressure. Hence, at early stage of kidney disease, patients will have high blood pressure to different degree.

2011/12/12

Chinese Therapy for Renal failure

Root cause or renal failure
As you know, the basic unit of the kidneys is nephron, which is in charge of filtering metabolic wastes in the blood. Each nephron is made of a renal corpuscle and a tubule. Maybe you are not familiar with these terms, but I guess you know glomerulus. In fact, glomerulus is a part of renal corpuscle. When people are told that they have developed kidney disease, actually it means that glomerulus or/and renal tubules is damaged by some reasons, say high blood pressure, high blood sugar, deposition of immune complex, etc. And this damage actually works on renal functional cells in glomerulus and renal tubules. As a result, some renal functional cells are impaired and some are sclerosed (dead). In this case, wastes like creatinine, uric acid, BUN, etc cannot be filtered out. In addition, some renal cells cannot secrete necessary substances as usual, for example, erythropoietin. Without insufficient erythropoietin, people will develop anemia.
From above, we can conclude that the root cause of renal failureis damage or sclerosis of renal functional cells.
Introduction of Chinese therapy
Then I am going to tell you how Micro-Chinese Medicine Osmotherapy and Stem Cell Transplant focus on solving root cause of renal failureand therefore can improve kidney function.
Micro-Chinese Medicine Osmotherapy refers to Chinese herb medicine plus a new technology. It is not an oral medicine but an external one. Chinese herbs are shattered and then permeated into renal lesions with the help of an osmosis device and penetrant. Ingredients of this medicine firstly can clear up the blood by doing with inflammation and coagulation in the blood as well as degrading extra cellular matrixes formed by sclerosed renal functional cells. Meanwhile, some herb medicines stimulate the damaged renal functional cells to self repair and provide necessary materials of self-repairing. As renal functional cells repair, kidney function is improved. Besides, some herbs have effect in lowering blood pressure, relieving anemia and edema and improving immunity. In this case, when people are using Micro-Chinese Medicine Osmotherapy, they don’t have to take lots of oral medicines.

What is the Life Expectancy for Stage 5 Kidney(Renal) Failure

The life expectancy can range from months to several or many years, depending on the patients' specific illness condition.
The life expectancy is the best among young patients with no heart disease or other severe complications. If complications of dialysis such as hypotension, arhythmia and hypoxemia can be well handled, then the life expectancy can be possibly prolonged.
But for those with combined heart diseases and other severe vascular diseases, complications of dialysis and end-stage renal disease such as renal anemia, metabolic disorder and high blood potassium can shorten the life expectancy. In such cases, even a kidney transplant is not recommended because cardiovascular diseases can be aggravated when heavy dosage of immunosuppressive agents are adopted or infections occur in the transplantation.
Also, according to a recent medical report, life expectancy is better in those with more remaining kidney function than others, even if dialysis(whether peritoneal dialysis or hemodialysis) is adopted.
In moat cases, when patients just begin dialysis, there is still some remaining kidney units. But by relying on dialysis and leaving the remaining kidney units alone, the kidneys will gradually get failed and atrophied. With this course(long or short), patients will have to undergo dialysis more and more frequently and will have higher chances of suffering from infections, cardiovascular diseases and malnutrition, which can be life-threatening.

How are Diabetes and Kidney Failure Interlinked with Each Other

 Kidney failure led by diabetes is usually more complex and dangerous then other kidney diseases, even after the initiation of dialysis and kidney transplant, diabetics tend to go on much worser than others.
Then how are Diabetes and kidney failure interlinked with each other?
First, Diabetes can cause renal failure. The culprit in the progression into end-stage renal failure is the high blood glucose, which forces the kidneys to work beyond its capacity so as to excrete the excessive sugar out, thus gradually damaging renal capillaries. High blood glucose also slows down blood flow and intensifies blood concentration, causing deposits of excellular matrix in glomeruli and thickening glomerular basilar membrane. Over time, more and more glomeruli are damaged and diffuse glomerular sclerosis develops, causing increasing amount of protein in urine.
Besides, high blood pressure, whether primary or secondary to diabetes, is another important factor that deteriorate kidney condition. Diabetics with high blood pressure usually have a poorer prognosis than others. Another factor that increases chances of getting renal failure is family history of kidney diseases, but the genetic rate varies.
The earliest sign of diabetic kidney disease is microalbuminuria, which refers to protein in urine between 30mg/24h to 300mg/24h. Heavy proteinuria(>3.5 g/24h) and overall swelling usually indicate that the disease has developed into clinical stage and will develop into end-stage renal failure rapidly.
How does diabetes affect the patients at end-stage renal failure?
In end-stage renal failure, patients are faced with both complications of kidney failure(such as vomiting, nausea, poor appetite, swelling and short breath) and diabetic complications(such as heart disease, retinopathy and neuropathy). So the situation is hard to be controlled. Also, due to lowered immunity, diabetics are also more likely to get infections, which, if occurs, can aggravate heart disease and can be life-threatening. Thereby, diabetics on dialysis usually have a poorer prognosisthan other kidney diseases.

2011/12/09

How to Treat IgA Nephropathy

IgA Nephropathy is a set of chronic glomerular diseases which have the same immunopathology characteristics. 40%-50% of patients got gross hematuria or microscopical hematuresis. 35%-40% of the patients have manifestations like microscopical hematuresis together with proteinuria. The others have symptoms of nephrotic syndrome or renal failure.
Treating IGA Nephropathy sclerosis with hormone, triptolide and cyclophosphamide to anti-inflammation is not enough to improve ischemia and anaerobic condition, and can’t repair glomerular filtration membrane effectively and recover its normal functions. It is obvious that hormone, triptolide and cyclophosphamide can play provisional roles as follows: first restrain the generation of receptor and control the damage and progress of inflammation; second deal with urine protein and occult blood in symptomatic treatment. In fact, these drugs can’t repair the damaged renal intrinsic cells, so the source of the trouble isn’t eliminated.
Even if proteinuria and occult blood are disappeared after taking medicine in focal proliferous sclerosing IgA nephropathy, due to the disease fundamental lesion can’t be treated, the lesion of renal intrinsic cells are still in. Thus, proteinuria and occult blood will repeat due to reiterative immune complex deposit. Therefore, what should we do to treat IGA nephropathy? The most fundamental key to treat IgA Nephropathy is to repair damaged renal intrinsic cells.
After many years’ research and experiment, a characteristic treatment has been established in China Shijiazhuang Kidney Disease Hospital: Micro-Chinese Medicine Osmotherapy. Actived Chinese Medicine substance contributes its effects in improving internal environment. It can also provide various nutritions to renal intrinsic cells. In the end achieving the goal of repairing intrinsic renal cells, recovering renal functions and avoiding the repeating disease.

Treat Renal Failure and Lower High Creatinine Level in Blood Apart from Dialysis

Micro-Chinese Medicine Osmotherapy is the special treatment method of renal failure and lowering creatinine level in blood.
This therapy aims to repair damaged kidneys by dilating blood vessels (to improve ischemia and anoxia condition and kidney burden) and anti-inflammation (to protect the normal kidney cells from being damaged).
What really counts is that the kidney cells will be repaired gradually. After the damaged kidney cells are repaired by this therapy, the necrotic ones can be replaced by new cells differentiated by stem cells,
Stem Cell Transplant is the new treatment method of renal failure and lowering creatinine level in blood.
New and healthy cells can be created by stem cells to replace the dead kidney cells.
With the help of combination of Micro-Chinese Osmotherapy and Stem Cell Transplant, there are more normal kidney units. And then kidney function will be improved so as to remove toxin in body and then decrease the high creatinine level. Once their kidney function is improved fundamentally, they are more likely to get rid of dialysis or lessen the frequency of receiving dialysis at least.

Prevent Renal Failure from Polycystic Kidney Disease (PKD)

In China, Polycystic Kidney Disease (PKD) can be controlled well by traditional medicine (TCM), which has a very long history of more than 2000 years. It is practiced by about 1/5 population of the world. Even many people in the United States, Australia, Europe and Canada regard Chinese medicine as their first line of defense in maintaining health and combating diseases. Back of centuries of empirical experience, the huge pharmacopeia contain thousands of substances include plant, animal, mineral origin, most of them herbs, some of which can restrain the growing of cysts on kidney effectively. In recent decades, new external application method of TCM on treating PKD is developed to avoid bitter taste and little side effects of some traditional herbs. It is called Micro-Chinese Medicine Osmotherapy, which is practiced a lot and effects of it has been proved.
The herbs, which have effects on preventing PKD developing will be micronized first and then osmosed into kidney lesions from skin.
The medicine could be taken home to be used continuously without any side effects by external application. Then the cysts can be controlled well. You don’t need to worry about it all day long.

2011/12/03

Specialized Chinese Medicine Therapy in Chronic Renal Failure

As to this problem, what are the opinions of experts from Shijiazhuang Kidney Disease Hospital?
In our opinion, it is possible to stop the progress of Chronic Renal Failure. If we can find out the source of the disease, we can treat it perfectly.
Our treatment in Chronic Renal Failure is combined traditional Chinese medicine and western medicine, the main treatment is not traditional Chinese Medicine therapy but modern Chinese Medicine therapy. We treat Chronic Renal Failure with Micro-Chinese Medicine Osmotherapy, not only treat the symptoms in clinic but also treat the primary source of the disease, so achieving the perfect effect in clinic. For many years’ research, we found that the reason why the there are many symptoms like proteinuria and hematuresis , edema and high blood pressure, anemia and increasing creatinine in chronic nephritis especially chronic renal failure is that there are micro-circulatory disorders, inflammatory response, condition of ischemia and hypoxia, cruor mechanism hyperfunction, generation and degradation imbalances of extracellular matrix. If this lesion continues, renal functional cells will change from withering to necrosis, and its number will be smaller and smaller, this progress is called renal fibrosis. Abnormal hyperplastic extracellular matrix namely fibrous tissue will be more and more, they cover and replace the renal intrinsic cells gradually. So to speak, renal fibrosis is the primary source of Chronic Renal Failure. Now you know, if the progress of renal fibrosis isn’t stopped, all of the symptoms will not disappear thoroughly. But the actual situation is that there is none of the western medicine in recent medicine can stop the fibrosis progress. While traditional Chinese Medicine is too weak to stop renal fibrosis. Only 25% of traditional Chinese Medicine which we have taken can reach to the renal lesion.
Aiming at the above results and analysis and after many years research, we have developed Micro-Chinese Medicine Osmotherapy. The core technology of Micro-Chinese Medicine Osmotherapy is to make the effective prescriptions of kidney disease super-finely shattered. Then with the help of effective penetrant and osmosis devices, the effective medicines are permeated into kidney lesions by external application, thus achieving the goal of blocking renal fibrosis. The Micro-Chinese Medicine has the effects as follows:
1. dilating blood vessels 2. anti-flammation 3. anticoagulation.
Micro-Chinese Medicine can eliminate lesion factors of renal fibrosis, so renal fibrosis progress is stopped. Micro-Chinese Medicine Osmotherapy provides nutritions to damaged renal intrinsic cells. And improve these cells to restore their functions. Besides, Micro-Chinese Medicine Osmotherapy can play the role as dredging meridians, conditioning organs and enhancing sufferers’ immunity.

The Treatments of Kidney Failure Caused by Hypertension

So far, there are six kinds of hypotensor: diuretics, Bata Blocker, Calcium Antagonist, Alpha Blocker, Angiotensin-Converting Enzyme, Angiotensin Receptor Antagonist, which are all chemical drugs or medicines. They are effective in treating Acute Hypertension or hypertensive crisis as well as perioperative hypertension. However, those medicines tend to cause blood pressure to fluctuate greatly, which will affect the metabolism of water, electrolyte, blood lipid, blood glucose and so on. For instance, too fast lowering blood pressure will make heart fail in pumping enough blood for vital activities and especially damage brain and kidneys which are rich in capillaries. Western medicines mainly dilate blood vessels to lower blood pressure but they are helpless in improving high lipid, high viscosity in blood, angiosclerosis along with damaged organs. As reported, Kidney Failure and Heart Failure take main responsibility for the death of patients with hypertension. Therefore, the blood pressure can not be controlled stable and the persistent wavy blood pressure will make those patients have hypotensor in their whole life.
Hypertension and Kidney Failure
Hypertension is the main factor of deteriorating Kidney Failure. As kidneys are rich in capillaries, renal tissues, especially kidney tubules, are sensitive to the lack of blood and oxygen resulting from fluctuating blood pressure. Actually, Kidney Failure is the result of the interaction of hypertension and Kidney Failure. Most patients with Kidney Failure are accompanied with hypertension, while hypertension is destined to damage kidneys. However, the people with hypertension seldom have the ideal of their lost renal function. The effective medicines can lower blood pressure gradually and protect other organs at the same time.
Micro-Chinese Medicine Osmotherapy
In order to lower hypertension forever, we must solve the problems of thick blood and sclerotic blood vessels. Chinese herbal medicines in Micro-Chinese Medicine Osmotherapy boast for regulating blood lipid, blood glucose and blood pressure, such as Kendir and Glossy Ganoderma. Some other substances in Micro-Chinese Medicine Osmotherapy are able to not only dilate blood vessels but also soften them. Moreover, it is a long and chronic course of lowering blood pressure through Chinese traditional medicines, which is stable and harmonious. The side effects are little, because Micro-Chinese Medicine Osmotherapy applies external technology and equipment not oral methods, avoiding the discomforts of intestine and abdomen. At the same time, it can enhance the immunity and protect kidneys and other organs from being damaged.

2011/10/16

Normal Range of GFR

As we know, GFR (Glomerular Filtration Rate) is the most important standard of renal function and the degree of kidney disease. To people who have kidney disease or not, they want to know the normal range of GFR. One thing you should know that the normal range is a little different in different hospital for the reason of calculating, machine and so on.
According to the National Kidney Foundation, normal range of GFR is from 90 - 120 mL/min. Older people will have lower normal GFR levels, because GFR decreases with age. It is easy for people to understand that kidneys become weak with the age increasing, even for the normal people.
Normal value ranges can vary slightly among different laboratories. So, do not feel surprise to your result of GFR. Talking to your doctor about what your specific test results mean.
In a word, GFR is the best test to measure your level of kidney function and determine your stage of kidney disease. Your doctor can calculate it from the results of your blood creatinine test, your age, race, gender and other factors.
Comparing the normal range of GFR, there is abnormal range of it. GFR is a mirror for evaluating the condition of kidneys. What Abnormal Results Mean Levels below 60 mL/min for 3 or more months are a sign of CKD(Chronic Kidney Disease). Those with GFR results below 15 mL/min are a sign of Kidney Failure.
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What is Dry Weight among Patients with Renal Failure?

Dry weight is the ideal weight that patients want to have after dialysis. At this time, without swelling, patients have normal blood pressure and can breathe smoothly when lying. It is very important for doctors to evaluate the effect of dialysis patients take.
Dry weight is an approximate number given by doctors though two or four week’s observing the patient. Before dialysis, they will predefine a change of weight. If the patient have the symptoms like low blood pressure, fatigue, cramps and dizziness in or after dialysis, it predicates the number predefined is too low for the patient and the doctor will correct it in next dialysis. Accordingly, the symptoms like swelling and left heart failure show that the number is too high for the patient and the doctor will lower it next time. Though this adjusting, the suitable dry weight can be available.
That is why patients must weigh their weight before and after dialysis. What’s more, the weight of their clothes and shoes has to be taken into consideration. Without dry weight, the dewatering amount in dialysis is blind and will arouse many complications, such as low blood pressure in overdue dewatering or heart failure in incomplete dewatering.
After dry weight is fixed, attention must be paid to the increase of weight between two times of dialysis. As for patients with Renal Failure, water intake is usually more than it output, because of their oliguria or anuria. If the patients absorb too much water from daily meals, they also can have the symptoms like swelling or heart failure. What’s worse, in older to remove too much water, dialysis will remove so much weight that patients may feel uncomfortable. The symptoms of low blood pressure will occur. So it is better to control the ideal change of weight between two times of dialysis under 5%.
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2011/10/15

What Kinds of Food Lowers Creatinine Level

What Kinds of Food Lowers Creatinine Level
What Kinds of Food Lowers Creatinine Level

I have to say, creatinine level cannot be decreased by any kind of food. In other words, no matter what food patients eat, the creatinine level will rise.
More and more people are pursuing for health promotion by diet and aerobics. Some people even make their disease treated by diet therapy. It seems that some people benefit from diet therapy. In this condition, patients experiencing high creatinine level wonder what kinds of food can lower creatinine level.
A small amount of creatinine comes from food metabolism. After eating, creatinine will be produced. The more patients eat, the higher the creatinine level is.
However, it is impossible for patients not to eat anything. To solve this problem, patients have two choices. One choice is to make their damaged kidneys repaired since it is the kidney damage that results in the inability of kidneys to discharge creatinine in blood. The other choice is to receive dialysis as necessary.
Generally, if patients' creatinine level doesn't reach to 450 ummol/L, they are recommended to receive herbal medicine treatment so as to help repair the kidneys. Once the kidneys are repaired, the kidneys can discharge creatinine by themselves.
If patients' creatinine level reaches to 450 ummol/L, they are recommended to take dialysis to help remove creatinine. By this way, the creatinine level can be lowered for the time being. And then herbal medicines can perform the function to repair the kidneys on the basis of relatively clean internal environment.

Long-Term Complications of Hemodialysis (Ⅰ)

Depending on hemodialysis, some patients with end stage Renal Failure can have obvious treatment effect and their symptoms of end stage Renal Failure can be remitted immediately. However, besides some short-term complications, there are many long-term complications after hemodialysis.
Ⅰ High blood pressure:
This complication is related to retention of water and sodium, increased activity of rein-angiotensin system as well as excitability of sympathetic nervous system going up, etc.
ⅡLeft heart insufficiency:
Besides high blood pressure and retention of water and sodium, this complication is also associated with anemia, acidosis, internal fistula, electrolyte distribute and malnutrition, etc.
Ⅲ Coronary Disease:
Based on coronary arteriesarteriosclerosis, excessive ultrafiltration which can lead to coronary ischemia, is main cause of this complication
Ⅳ Pericarditis:
Pericarditis occurs two weeks after dialysis, which is called early stage Pericarditis, and if this complication appears after two weeks’ dialysis, we ordinarily calls it delayed Pericarditis.
ⅤPulmonary Edema:
Overloaded water causes this complication, and occasionally Congestive Heart Failure, Hypoproteinemia and increased permeability of capillary in lung play a role in arousing Pulmonary Edema.
Ⅵ Pleural effusion:
This complication is primarily exudative, which results from Heart Failure, retention of water and sodium, Nephrotic Syndrome and infection, etc.
Ⅶ Digestive tract disease:
This complication includes Esophagitis, Gastritis, Gastric Ulcer, delayed gastric emptying and gastrointestinal hemorrhage, etc.
Ⅷ Intestinal ischemia and intestinal infarction:
Patients with Hypertension, hyperlipidemia, Heart Failure or Diabetes Mellitus often have this complication.
Ⅸ Liver disease:
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2011/10/14

How the Chinese celebrate China National Day

China National day is an important day to the Chinese at home and abroad. On the day, many celebrations will be hold at every place in China and other countries where there are Chinese. Joining the festival, no Chinese people is not proud as a Chinese. If you are foreigner at other country on the day, you can also enjoy the happiness in festivities, but the local Chinese have their own ways to enjoy the day and their long holiday.
Traveling to other places with tourist attraction
There are many tourist attractions in China, including not only places of interests but also the scared places of Chinese revolution as well as the modern metropolises. A great movement of population is destined to happen on China National Day, because there is no time for local Chinese people to travel to those places and they can seek for something meaningful beyond their daily life in this long vacation. The scared places of Chinese revolution are the most popular spots on the day. They are visited by thousands of people every day. Parents usually bring their children here, some companies will arrange their staff to visit those places and some people come here for their certain belief. Facing those scared places, all people are reminded to cherish their life at present and remember how hard their peaceful life is created by martyrs.
The Chinese is a grateful nation. They are desiring for development but looking back to think over their faults as well as successes at the same time.
Shopping during the golden time
On China National Day, most local Chinese will have a long holiday of three to seven days. If the day follows Mid-autumn festival, the holiday will be up to ten days. It is really a long time enough to have a good rest. As for the young, they can put their busy work side and enjoy their hobbies temporarily. Thus all kinds of sales markets are extremely crowed and booming. All shopping malls will carry out their plans to promote sales. For instance, the prices of most sales will be much lower than that at other times. Chinese people are usually able to buy their favorite commodities of satisfied price and quality.
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Ganoderma in Lowering Blood Fat

Ganoderma in Lowering Blood Fat
Ganoderma in Lowering Blood Fat
High blood fat is one of the most dangerous factors among patients with Polycystic Kidney Disease (PKD), which may cause many severe complications like cardiovascular disease. It is common for those patients to have some medicines to lower fat in blood, but it is inevitable that most of those medicines will damage liver. Ganoderma is an important herbal medicine in china, which boasts for the function of lowering blood fat without harming liver.

Generally speaking, Ganoderma can remove the poisonous substances and clean blood to lower the viscosity of the blood. There are six functions of Ganoderma in lowering or reducing fat in blood.
1. Ganoderma can reduce cholesterol, triglyceride, β-lipoprotein and LDL (low density lipoprotein) and increase HDL (high density lipoprotein). It is reported that HDL carries excessive fat from blood to liver where those fat is transformed into cholate and drain out though biliary tract. HDL is good at lowering fat in blood and preventing arteriosclerosis.
2. Improving the disorder of hemorheology, Ganoderma dredges blood vessels and promotes blood circulation, lowering the viscosity or coagulability of blood.
3. Combined with other conventional medicines will enhance the therapeutic effects of lowing blood fat.
4. As a traditional Chinese herbal medicine, the function of Ganoderma involves in the severity of high blood fat and the length of time in which Ganoderma is had. If the fat is very high in blood, Ganoderma may can not lower it immediately and remove the possibility of sudden death of the patients. Ganoderma needs a long time to regulate blood fat in daily life, so it has a good therapeutic effect in large doses among patients whose fat is slightly or moderately high in their blood.
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2011/10/12

Functions of Acupuncture and Moxibustion Therapy


Acupuncture and Moxibustion Therapy is an oldest treatment method originated from ancient China. Nowadays, this natural treatment method has widely spread to the world. Acupuncture and Moxibustion Therapy is very good for patients who have blood vessels problems or internal organ problems.
The functions of Acupuncture and Moxibustion Therapy:
1. Acupuncture and Moxibustion Therapy has the function of dredging the channel.
Acupuncture and Moxibustion Therapy can effectively improve blood circulation, promote metabolism, dredge meridians, Qufeng desiccant, analgesia to cold, and enhance the body resistance to disease. Relaxing channel meridians is a basic and direct function of Acupuncture and Moxibustion Therapy, which can relieve symptoms such as pain, numb, swell and eccymosis etc.
Main and collateral channels can be explained both in viscera and podomere. This therapy can promote the blood circulation and provide people inner strength.
2. Acupuncture and Moxibustion Therapy has the function of mediating Yin and Yang.
Yin and Yang are two opposing principles in nature. Men belong to the side of Yang and women belong to the side of Yin. A family should make up of man and women, which can maintain a harmonious condition. As for human body, Yin and Yang should keep a balance or people will show discomforts.
Acupuncture and Moxibustion Therapy can mediate the balance of Yin and Yang, which is the final goal of this therapy. The occurrence of each disease is complex but it can be categorized into Yin and Yang disorder. This function can improve the coordination of Yin Channel and Yang channel and points as well through manipulation of acupuncture.
3. Acupuncture and Moxibustion Therapy have the function of strengthening body resistance and eliminating pathogenic factors.
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Medicated Bath in Treating Kidney Diseases


Medicated bath is also called Hydrotherapy, which can date back to Zhou dynasty over 3000 years ago. Since Qing dynasty, medicated bath has been adopted by Chinese medical specialists in treating or preventing some kinds of disease like Kidney diseases. Medicated bath inherits the principle of enhancing or regulating human being its own immunity to guard against diseases.
The functions of skinMedicated Bath in Treating Kidney Diseases
From the modern point of Chinese medical science, skin is the natural filtration membrane with acreage of 1.6 cm2 almost equaling to the total filtration area of glomeruli. The skin of human being owns many blood capillaries as well as two to four million sweat glands. That is to say, there are about 130 sweat glands on every square centimeter. In spite of one sweat gland weighting 30~40 ug, their total weight equals a kidney about 100g. In other words, skin has the similar functions of kidney, such as secretion and regulation. Sweat from skin contains about 99% water and 1% objects including sodium chloride, urea, creatinine, ammonia, uric acid etc, which means that skin can drain out some metabolic wastes. Besides secretion, skin plays an important role in regulating electrolyte, water and other substances, because it is also able to hold water and reabsorb something. Patients with uremia or at the End Stage Kidney Failure will have ureafrost and skin itch, because their renal function have failed and the deposited metabolic wastes will find access of skin to drain out.
Scientificity of medicated bath in treating Kidney Diseases
The hot water in medicated bath will dilate the pores and blood vessels. The effective medicines are absorbed by skin and reach the lesion though blood circulation, treating the disease inside and outside. Since ancient time, medicated bath has been used to activate blood circulation, dissolve blood stasis, prevent cold, detoxify toxins, ease swellings and pain, regulate immune system, maintain health and so on. It is proved that medicated bath can increase certain immune globulin in blood and enhance the flexibility and activity.
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What is Polycystic Kidney Disease?


Polycystic Kidney Disease (PKD), also called Potter syndrome or Perlman syndrome, is a genetic disorder, which can be divided into Autosomal Dominant Polycystic Kidney Disease (ADPKD) and Autosomal Recessive Polycystic Kidney Disease (ARPKD). ARPKD can be diagnosed typically in the first few weeks after birth and the children are usually unable to live out their childhood. So we mainly talk about ADPKD here.
Causing genes
The Autosomal Dominant Polycystic Kidney Disease is caused by two genes: ADPKD1 and ADPKD2. ADPKD1 lies in the short arm of chromosome 16, while ADPKD2 is located on the short arm of chromosome 4. As is reported, patients with ADPKD2, especially the female patients, tend to have less severe ill conditions than patients with ADPKD1. The signs or symptoms of ADPKD1 like kidney function declining or renal failure may appear later than that of people with ADPKD2. ADPKD2 is responsible for 90% cases of Autosomal Dominant Polycystic Kidney Disease. With autosomal dominant inheritance, there is a 50% chance that the disease will pass to the children of one patient with PKD.
The general course
Patients are born with cysts which are too small to check out. At their twenties, cysts usually have began to grow but without any visible or perceptible symptoms. When patients reach their thirties or forties, cysts in their kidneys will get bigger shapely. Blood pressure becomes slightly high among those patients, which can further speed up the deterioration of PKD. After about ten years of high blood pressure, namely at their forties, patients will have the tumid cysts and severe symptoms occur such as hemature, proteinuria and flank pain. The renal function begins to fail. After the age of fifties, PKD will cause real insufficiency or renal failure as well as cysts in liver and other organs. The severe complications will also occur such as cerebral aneurysm and heart diseases, which take the main responsibility for the death of patients with PKD.
Clinical symptoms
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2011/10/07

What does the Fourth Stage Kidney Failure Mean?


Kidney Failure can be divided into five stages according to GFR (Glomerular filtration rate). At the Fourth Stage, GFR is 30 ml/min to 15 ml/min, Creatine tops 443 umol/L to 707umol/L and BUN (blood urea nitrogen) between 17.9 mmol/L to 28.9 mmol/L together with the sharply decreasing functions of kidney, electrolyte disturbance and acidosis.
Patients with this stage of Kidney Failure may be getting prepared to discuss treatment options such as dialysis. In traditional treatments, Kidney Failure with GFR less than 25 ml/min is impossible to stop its deteriorating and patients only can take dialysis or kidney transplantation. Dialysis actually replaces the functions of real kidneys to remove the waste and water deposition, while kidney transplantation is to replace the damaged real kidney by another kidney.
Dialysis can merely ease the symptoms and can not improve the conditions of kidney. Although kidney transplantation is carried out with a high successful rate, it has a same high risk of failing and allergy, which both bring difficulties to the patients who want to take other treatments.
Micro-Chinese Medicine Osmotherapy and Stem Cell Transplantation give new hope to patients with Fourth Stage Kidney Failure. Even if GFR is less than 25 ml/min, the quality of patients with Fourth Stage Kidney Failure would be improved through the adjustment of Micro- Chinese Medicine Osmotherapy and the reparation of Stem Cell Transplantation.
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Complication of Peritoneal Dialysis


In clinic, peritoneal dialysis can delay the loss of surviving renal function, and improve the quality of patients’ life. The indications of peritoneal dialysis include Acute and Chronic Renal Failure which are caused by all kind of kidney disease. In addition, liver failure and acute toxic diseases also can be treated by peritoneal dialysis. However, there are some complications which may occur during peritoneal dialysis.
Complications of peritoneal dialysis
ⅠPeritonitis
According to improvement of connection technology and attaching importance to nursing exit, infections which are related to peritoneal dialysis have been well controlled, the incidence of which obviously decreases. Peritonitis can lead to severe loss of protein, peritoneal adhesion, peritoneal thickening and peritoneal dialysis failure as well as blocking catheter, which can threaten life.
ⅡAbdominal pain
Abdominal pain may result from high hypertonicity dislysate, high or low temperature of dislysate, excessive dialysate and celiac infection as well as catheter movement.
ⅢObstructed drainage and blocking catheter
Warping, movement, and blocking by fibrin, blood clot can lead to this complication. What’s more, too much gas in enteric cavity or abdominal cavity is another cause.
Ⅳ Swelling and pulmonary edema
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2011/10/04

Sexual Life and Dialysis


Can Patients who undergo dialysis have sexual life? This is a common question we often meet. Generally, patients with stage 4 Renal Failure will have hyposexuality, because the pituitary gland can not receive the signals from testes and ovaries to produce sex hormones. And patients with end stage Renal Failure often have impotence and infertility in men, premature menopause in women, and low or totally absent sex drive in both genders. In addition, most patients with end stage Renal Failure have anemia, which is another negative influence on libido.
Large amount of toxins and excessive water can be discharged when patients just begin to take dialysis, so that physical function may return to normal level, which will be accompanied with normal physiological requirement. However, this condition will change during long term dialysis. In general, 35% male patients who are taking dialysis will have further decline of sexual function, the proportion of female patients is 25%. Only 9% male patients and 6% female patients will improve their sexual function.
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Announcements of Peritoneal Dialysis


Contrast to medical condition of end stage Renal Failure in China, in western countries patients will just wait for dialysis and kidney transplant. And depending on the development of technology more and more patients with end stage Renal Failure accept peritoneal dialysis, which is easy to be operated and be taken at home. What kinds of patients are suitable for peritoneal dialysis? And what should we pay attention to the place of peritoneal dialysis?
Peritoneal dialysis should be as the first choice of them who are corresponding with one or more condition.
Ⅰ Patients who are older than 65 years old
Ⅱ Patients who have cardiovascular diseases, such as Angina Pectoris, Old Myocardial Infarction, Cardiomyopathy and arrhythmia, etc.
Ⅲ Patients who have Heart Failure, low blood pressure or uncontrolled high blood pressure
Ⅳ Patients who once had cerebrovascular accident such as cerebral hemorrhage and cerebral infarction
Ⅴ Patients with Diabetes Mellitus, especially accompanied with ocular fundus changes or peripheral neuropathy
Ⅵ Children
Ⅶ Patients who had fistulation failure for several times
Ⅷ Patients who have obvious bleeding tendency.
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2011/09/30

Coffee or no Coffee

Coffee or no Coffee
Coffee is a brewed beverage with a dark, slightly acidic flavor prepared from the roasted seeds of the coffee plant, colloquially called coffee beans. The beans are found in coffee cherries, which grow on trees cultivated in over 70 countries, primarily in equatorial Latin America, Southeast Asia, South Asia and Africa. Green (unroasted) coffee is one of the most traded agricultural commodities in the world.[1] Coffee can have a stimulating effect on humans due to itscaffeine content. It is one of the most-consumed beverages in the world.

I believe that a lot of people fall in love with coffee, and I am one of them. However, coffee is hard on kidney when you already have Renal Failure. Some patients with Renal Failure strictly follow it. And some people may oppose to it. This is an old argument. Why do I say coffee is bad for patients with Renal Failure? There are three reasons as follow.
Ⅰ Coffee contains much caffeine, which is common sense. Many patients with Renal Failure maintain that caffeine has not bad effect on kidney disease, but we should not forget that coffee can always let spirit rouse, and then difficultly in falling asleep. Low quality of sleep and body can not get well rest, which may arouse the relapse of kidney disease.
Ⅱ Coffee restrains the absorption of ferrum, which is reported by dietitian. Patients with Renal Failure may know there will be renal anemia when Chronic Kidney Disease (CKD) develops into stage 3. At this moment, coffee plays a role in stopping the absorption of ferrum, which is bad for treating renal anemia
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2011/09/18

The Confusion of a Patient with Renal Failure


Here is a message from a patient with Renal Failure, in which she expressed the confusion about her medical conditions.
Hi doctor, my creatinine clearance was 17.26ml/mins, my 24 hour urinary protein was 342 and the machine value was 21.6, but I have no symptoms of a kidney failure person, like blood in urine, swelling of feet and shortness of breathe. I want to know why and I wonder where I stand.
From what she said, we can feel that she is very surprised about the severity of her disease and confused why she did not present some symptoms of Renal Failure. Actually, many patients have the similar experience that no obvious symptoms attract their attention, but it has been at the late stages of Renal Failure when it is diagnosed.
Renal compensation
The kidneys in the body boast a great compensation. Even if we lost one kidney, we still can feel normally. Only when more than half function of kidney fails emerge the obvious symptoms. The common urine test includes creatinine, ptrotein and blood in urine. The patients usually never know about creatinine clearance test or GFR (glomeruli filtration rate). GFR is the best one reflecting the function of kidney and even more precise than the value of clearance creatinine test.
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2011/09/14

The causes of Chronic Renal Failure


Do you know Chronic Renal Failure? 
The causes of Chronic Renal Failure
Chronic Renal Failure refers to the damaged renal parenchyma with various causes. Kidney atrophies obviously, which can not maintain renal fundamental function. The clinical manifestations of Chronic Renal Failure are retention of metabolin, imbalance of water, electrolyte and acid-base as well as the involvement of the whole body.
Ⅰ Common causes:
① Infectious nephropathy: Chronic Pyelonephritis, nephrotuberculosis, etc.
② Chronic glomerulonephritis: IgA Nephropathy, Mesangial Proliferative Glomerulonephritis and focal segmental sclerosing glomerulonephritis, etc.
③ Toxic nephropathy: toxic nephropathy due to heavy metals, nephropathy due to analgesics, etc.
④ Vascular renal lesion: renal vascular hypertension, hypertension, renal arterial sclerosis, etc.
⑤ Genetic kidney disease: Polycystic Kidney Disease, Alport syndrome, etc.
⑥ Systemic disease: renal damage due to vasculitis, Multiple Myeloma and Lupus Nephritis,etc.
⑦ Renal damage due to abnormal metabolism: Diabetic Nephropathy, Amyloidosis Kidney Disease and Gouty Nephropathy, etc.
⑧ Obstructive Nephropathy: ureteral obstruction, reflux nephropathy and lithangiuria,etc.
Ⅱ Pathogenesis
① Surviving nephron theory: The majority of nephrons are damaged by various causes. And the surviving small part of nephron which is slight damaged and has normal function, has to do compensative work to maintain normal needs of the body, which causes the surviving nephrons to become compensatory hypertrophy. On this condition, both glomerular filtration rate and the function of renal tubules will increase. If this condition can not be prevented, glomerulosclerosis will occur. At last, the surviving nephrons will gradually decrease, as well as renal function.
② Uremia toxins theory: Uremic toxins may be the various substances which are accumulated in the stage of Renal Failure, such as PTH, phosphorus, urea, creatinine, guanidines, phenols and indole, etc. These substances have the following features:
1. Concentration content in the body is higher than that of normal.
2. High content is related to Uremia.
3. These substances can be detected by chemical analysis and quantitative determination.
4. The content of these substances is similar with that of the patient with Uremia.
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2011/09/13

Is My Medical Condition dangerous?


Do you know Medical Condition dangerous?
Is My Medical Condition dangerous?
Diabetes is an important primary disease of Kidney Failure, in particular, II type Diabetes. High blood sugar is undermining kidneys. As Diabetes can arouse many complications, the problems of kidney are usually ignored by most of patients. They often find Kidney Failure in checking or treating high blood pressure or other symptoms of Diabetes. Without the ideals about Diabetic Nephropathy and Kidney Failure, most patients pay little attention to their medical conditions about kidneys.
There is a case of patient who is suffering from Diabetes and has problems of kidney.
I have had Diabetes for five years. When I was hospitalized for high blood pressure, urine protein shows + + + in my test report. My doctor said nothing else except advising me the injection of protein. Without flank pain and fatigue, I am just unwilling to eat something. I want to know whether my medical condition is dangerous or not.
Kidney damages caused by Diabetes can be separated into five courses: high glomeruli filtration rate, damaged glomeruli without symptoms, microalbuminuria, clinical proteinuria and the End Stage Kidney Failure. As kidney functions are normal in early two stages, Diabetic Nephropathy includes microalbuminuria, clinical proteinuria and the End Stage Kidney Failure, excluding high glomeruli filtration rate, damaged glomeruli without symptoms.
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2011/09/05

The Dilemma of Kidney Transplantation in China


The Dilemma of Kidney Transplantation in China
Recently, a young man has attracted the attention of many Chinese people. This young man, called Liu Fei, has being suffering from the End Stage Renal Failure for one year. His mother’s kidney is suitable to him for transplantation, but his mother refused and left home, which provokes a heated discussion among Chinese people.
Liu Fei was born in a poor family in Sichuan province. Their life mainly depends on the money made by his parents in taking part time jobs. When he was diagnosed as the End Stage Renal Failure, he left school and leased a tricycle to make money for dialysis. In China, there are many people without medical care in some poor areas, which means that some treatments are usually unaffordable to them, such as dialysis and kidney transplantation. The problem of kidney transplantation lies not only in the shortage of money but also in the limited kidney source. Chinese people who are unwilling to donating their kidney is not the persons without loving hearts but they owning a traditional thought that they must have a intact body to rebirth after their death and their children consider it is an important filial piety to keep their parents in whole bodies. In addition, many people hesitate to donate their kidneys because they think it is harmful to their health and may make them lose the ability of working.
Condemned by so many people, the mother of Liu Fei expressed her thought that if she donates her kidney to her son, there will be two patients in this poor family and they can not afford the medical fee after transplantation. Maybe this mother indeed has no choice but to make money and wait for another suitable kidney towards her son, or maybe she is scared to take the responsibility as a mother, but it is really a dilemma in China among patients with the End Stage Renal Failure. Besides complaining the underdeveloped economic conditions, what else can we do? Is there really no other choice for those patients apart from kidney transplantation and dialysis?
Actually, according to each patient’s medical conditions, as long as their surviving nephrons are in protection and the damaged nephrons can be recovered enough or even partially, there is a chance for them to get rid of dialysis, prolong their lives and even need not to receive kidney transplantation.
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