Edema is an important clinical manifestations of the nephrotic syndrome, adult serum white to white, <3 g to edema, but children do not necessarily edema in 1 g%. Edema of the distribution of adult mainly subcutaneous, only edema side hydrothorax and children to the eye, often hydrothorax and ascites, but the foot edema, which may be tissue tension the sake of children's feet. Facial swelling with anemia pale looking to make up a typical "renal face. Therefore, parents should pay attention to the emergence of edema, the next well-known kidney disease hospital for everyone to talk about children with nephrotic edema.
Children with nephrotic edema is due to severe proteinuria (urine foam), lower serum albumin, plasma osmolality decreased intravascular fluid into the tissue gap caused by the effective hypovolemia, a nearly spherical cells stimulated renin - angiotensin hormone - aldehyde and ketone-axis active so that the kidney further retention, retention of water, edema to occur and develop.
But one thing to note, edema of the severity of the nephrotic syndrome severity, duration, and the prognosis is not directly related to severe edema does not determine prognosis.
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