Iga nephropathy is mesangial proliferation and mesangial area was significantly iga deposition is characterized by a diffuse group of glomerular diseases more common in older children and youth, male to female ratio of 2:1. iga nephropathy onset before the children more often the incentive for upper respiratory tract infection induced by diarrhea, urinary tract infection cases.
Clinically, children iga nephropathy symptoms of diversification, the most common with hematuria.
Only microscopic hematuria to nephrotic syndrome, may be the onset of the performance, between the clinical phenotype in the course of mutual transformation, but in the course of the disease in its clinical manifestations may change each other.
In general, 80% of children iga nephropathy symptoms of gross hematuria as the starter, North America and Europe, the high incidence in Asia, often, and upper respiratory tract infection related (Berger disease), and upper respiratory tract infection a very short time intervals (24 ~~ 72h) even a few hours after hematuria, and more swollen tonsils, but after the tonsillectomy, most children with gross hematuria to stop seizures. [So, I would like to ask the experts, click on Free Consultation]
Also, some children manifested as hematuria and proteinuria, hematuria, either for episodes gross hematuria, microscopic hematuria, proteinuria, mostly mild to moderate, iga nephropathy with nephrotic syndrome manifested about accounted for 15% to 30% of the "three high and one low" performance is often very little merger before the onset of respiratory tract infections, some cases showed nephritis syndrome.
In addition to the above hematuria symptoms, children iga nephropathy symptoms of hypertension, renal insufficiency. Hypertension occurs in older adults accounted for 20% of children accounted for only 5%. Hypertension is an important indicator of kidney disease progression in iga, most accompanied by renal function deteriorated rapidly, and less than 5% of the iga nephropathy patients showed rapidly progressive glomerulonephritis.
Older children with recurrent episodes of gross hematuria, and many upper respiratory or intestinal infection, the incentive should be considered with iga nephropathy. The performance of a simple microscopic hematuria or gross hematuria or with a moderate degree of proteinuria, iga nephropathy should be suspected.
Therefore, nephropathy public treatment network special expert Zhang suggestions:
To fight the face of children's iga nephropathy, a kidney biopsy as soon as possible. Nephrotic syndrome, rapidly progressive glomerulonephritis syndrome, with hypertension and renal insufficiency performance, should be considered with iga nephropathy, but the diagnosis depends on renal biopsy. Also note that except for the other disorders can cause mesangial iga deposition.
